G-Hidrocortisone 100 mg/2 ml (IM/IV Injection)
100 mg vial: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Hydrocortisone |
| Company | Gonoshasthaya pharma ltd |
Title
- G-Hidrocortisone Tablet
Categories
- Medicine
- Pharmaceutical
DosageForm
- Tablet
- Injection
Indications
- Primary or secondary adrenocortical insufficiency
- Acute adrenocortical insufficiency
- Shock unresponsive to conventional therapy
- Congenital adrenal hyperplasia
- Hypercalcemia associated with cancer
- Nonsuppurative thyroiditis
- Rheumatic Disorders
- Dermatologic Diseases
- Control of severe or incapacitating allergic conditions
- Ophthalmic Diseases
- Gastrointestinal Diseases
- Fulminating or disseminated pulmonary tuberculosis
- Loeffler's syndrome
- Aspiration pneumonitis
- Hematologic Disorders
- Neoplastic Diseases
- Edematous States
- Acute exacerbations of multiple sclerosis
Pharmacology
Hydrocortisone inhibits prostaglandin synthesis by inhibiting the enzyme phospholipase A2. It reduces various vasoactive agents released during inflammation and controls the rate of protein synthesis.
DosageAndAdministration
- The initial dosage may vary from 20 mg to 240 mg per day
- Dosage requirements are variable and must be individualized
- Constant monitoring is needed in regard to drug dosage
- If, after long-term therapy, the drug is to be stopped, it is recommended that it be withdrawn gradually, rather than abruptly
- Adult initial dose for IM or slow IV injection or infusion is 100 mg to 500 mg, depending on the severity of the condition
- Children's doses vary by age
Interaction
- Drugs that induce hepatic enzymes may increase the clearance of corticosteroids
- Drugs such as Troleandomycin and Ketoconazole may inhibit the metabolism of corticosteroids and decrease their clearance
- Dose of corticosteroid should be titrated to avoid steroid toxicity
Contraindications
Severe systemic fungal infections and known hypersensitivity to any component of this product
SideEffects
- Cardiac arrhythmia
- Esophageal candidiasis
- Menstrual irregularity
- Decreased carbohydrate & glucose tolerance
- Fluid retention
- Increased appetite
- Weight gain
- Euphoria
- Mood swings
- Depression
- Insomnia
- Acne
PregnancyAndLactation
Should be prescribed in pregnancy and lactation only if absolutely required
PrecautionsAndWarnings
- Use with caution in patients with a history of peptic ulceration
- Use with caution in patients with congestive heart failure, hypertension, glaucoma, diabetic mellitus and epilepsy
TherapeuticClass
Glucocorticoids
StorageConditions
Keep below 30°C temperature, away from light & moisture, and keep out of the reach of children