G-Haemodialysis A (Dialysis Solution)

Indications

• Used in Haemodialysis

Composition

• Each 1 liter solution contains Sodium Chloride, Potassium Chloride, Calcium Chloride, Magnessium Chloride, Glacial Acetic Acid, Highly purified water

Pharmacology

• Calcium chloride used to prevent or treat negative calcium balance; regulates action potential excitation threshold
• Potassium chloride plays active role in nerve impulses, muscle contraction, renal function, acid-base balance
• Sodium chloride important in electrolyte and fluid balance, osmotic pressure control, water distribution; used for hydration, metabolic acidosis, haemodialysis
• Magnessium Chloride acts as cofactor in enzymatic reactions, depresses CNS, blocks neuromuscular transmission, produces anticonvulsant effects

Dosage & Administration

• Recommended dose: 5 liters concentrate per dialysis or as required

Interaction

• No known drug interactions

Contraindications

• Known hypersensitivity to any of the ingredients

Side Effects

• Fluid and electrolyte imbalance, hypovolemia, hypotension, muscle cramping

Pregnancy & Lactation

• Pregnancy Category not Classified by FDA

Precautions & Warnings

• Used for hemodialysis purposes only
• Do not use solution A or B alone
• Discard container in case visible solid particles inside

Therapeutic Class

• Haemodialysis solutions

Ingredients

• Sodium Chloride
• Potassium Chloride
• Calcium Chloride
• Magnessium Chloride
• Glacial Acetic Acid
• Highly purified water

Purpose

• Haemodialysis

Electrolytes Balance

• Maintains electrolyte balance

Nerve Impulse Conduction

• Plays active role in nerve impulse conduction

Muscle Contraction

• Facilitates muscle contraction

Carbohydrate Metabolism

• Affects carbohydrate metabolism

Gastric Secretion

• Plays a role in gastric secretion

Hydration

• Used for hydration

Metabolic Acidosis Treatment

• Used in treatment of metabolic acidosis

Hyperosmolar Diabetes Treatment

• Used in treatment of hyperosmolar diabetes

Infusion Diluents

• Used as diluents for infusion of compatible drug additives

Enzymatic Reactions

• Acts as cofactor in numerous enzymatic reactions

Protein Synthesis

• Involvement in protein synthesis

CNS Depression

• Depresses central nervous system

Anticonvulsant Effects

• Produces anticonvulsant effects

Hypersensitivity Reactions

• May cause hypersensitivity reactions

Visible Solid Particles

• Check for visible solid particles in container

Drug Classification

• Not yet classified by FDA

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