Lamocard 5 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levamlodipine maleate |
| Company | Drug international ltd |
| Also available as | Lamocard 25 mg tablet |
Indications
- Treatment of hypertension
- Lowering blood pressure
- Reducing risk of cardiovascular events
- Stroke prevention
- Myocardial infarction prevention
Pharmacology
- Dihydropyridine calcium antagonist
- Inhibition of calcium ion influx
- Selective effect on vascular smooth muscle cells
- Oral absorption with Tmax of 6-12 hours
- Bioavailability of 64-90%
- Volume of distribution similar to amlodipine
- Metabolism primarily mediated by CYP3A4
- Renal elimination
- Inactive metabolites
Dosage & Administration
- Oral route of administration
- Usual initial dose of 2.5 mg once daily
- Maximum dose of 5 mg once daily
- Dosage adjustment for elderly and hepatically impaired patients
- Pediatric dosage for ages 6-17 years
- Absorption unaffected by food
Interaction
- Impact of CYP3A inhibitors
- Limitation with simvastatin co-administration
- Potential interactions with immunosuppressants
- Absorption unaffected by food
- Avoidance of grapefruit products and natural licorice
Contraindications
- Contraindication in patients with known sensitivity to amlodipine
Side Effects
- Common: Difficulty in breathing, Dizziness, Reflex Tachycardia, Hypotension, Abdominal Pain, Edema
- Rare: Diarrhea, Back pain, Headache, Fatigue, Nausea
Pregnancy & Lactation
- Limited available data on use in pregnant women
- No observed adverse effects on breastfed infants
Precautions & Warnings
- Risk of symptomatic hypotension
- Potential worsening of angina and acute myocardial infarction
- Slow titration for hepatically impaired patients
Overdose Effects
- Excessive peripheral vasodilation
- Marked hypotension
- Reflex tachycardia
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store in a cool & dry place
- Protect from light & moisture
- Keep out of reach of children