Olapag 50 mg (Tablet)
Unit Price: ৳ 900.00 (1 x 10: ৳ 9,000.00)
Strip Price: ৳ 9,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Eltrombopag olamine |
| Company | Drug international ltd |
| Also available as |
Indications
- Treatment of thrombocytopenia in patients with persistent or chronic immune thrombocytopenia
- Treatment of thrombocytopenia in patients with hepatitis C infection
- Treatment of severe aplastic anemia
Pharmacology
- Small molecule thrombopoietin (TPO) receptor agonist
- Induces proliferation and differentiation from bone marrow progenitor cells
- Increases platelet production
Dosage & Administration
- Oral route of administration
- Can be taken without a meal or with a meal low in calcium
- Recommended starting doses for different conditions and patient populations
Interaction
- Drug interaction with medication - take eltrombopag at least 2 hours before or 4 hours after any medications or products containing polyvalent cations
- Drug interaction with food - take eltrombopag at least 2 hours before or 4 hours after any calcium rich foods
Contraindications
- Hypersensitivity to eltrombopag or any components
Side Effects
- Common side effects include anemia, nausea, pyrexia, ALT increased, cough, fatigue, headache, and diarrhea
Pregnancy & Lactation
- No sufficient data available to assess drug-associated risks for major birth defects or adverse maternal or fetal outcomes
- Breastfeeding is not recommended during treatment
Precautions & Warnings
- Increased risk of hepatic decompensation in patients with chronic hepatitis C
- Increased risk of death and progression of myelodysplastic syndromes to acute myeloid leukemia
- Risk of portal vein thrombosis in patients with chronic liver disease
- Monitor liver function and platelet counts regularly
Use in Special Populations
- Safety and efficacy in pediatric patients below the age of 1 year with ITP not established
- Safety and efficacy in pediatric patients with thrombocytopenia associated with chronic hepatitis C and refractory severe aplastic anemia not established
Overdose Effects
- Excessive increase in platelet counts may result in thrombotic or thromboembolic complications
- Consider oral administration of metal cation containing preparation to chelate eltrombopag and limit absorption in case of overdose
Therapeutic Class
- Haemostatic drugs
Storage Conditions
- Store in a cool and dry place below 25°C
- Protected from light
- Keep away from the reach of children