Lizolix 600 mg (Tablet)

Unit Price: ৳ 85.00 (1 x 10: ৳ 850.00)
Strip Price: ৳ 850.00

Medicine Details

Category Details
Generic Linezolid
Company Eskayef pharmaceuticals ltd
Also available as
Lizolix 400 mg tablet

Indications

  • Nosocomial pneumonia
  • Community-acquired pneumonia
  • Complicated skin and skin structure infection
  • Uncomplicated skin and skin structure infections
  • Vancomycin-resistant Enterococcus faecium infections

Pharmacology

  • Synthetic antibacterial agent
  • Oxazolidinones class of antibiotics
  • In vitro activity against Gram positive bacteria
  • Inhibits bacterial protein synthesis

Dosage & Administration

  • Oral route administration
  • Intravenous infusion administration
  • Dosage based on infection type and age
  • No dose adjustment necessary from IV to oral administration

Interaction

  • Reversible nonselective inhibitor of monoamine oxidase
  • Potential for interaction with adrenergic and serotonergic agents
  • Advice to avoid foods or beverages with high tyramine content

Contraindications

  • Known hypersensitivity to Linezolid
  • Contraindicated with monoamine oxidase inhibitors
  • Uncontrolled hypertension
  • Patients taking sympathomimetic agents
  • Patients with certain medical conditions

Side Effects

  • Most adverse events are mild to moderate
  • Common events include diarrhea, headache, and nausea
  • Other adverse events like hypertension and oral/vaginal moniliasis

Pregnancy & Lactation

  • Safety data in pregnant women
  • Consideration for benefits vs. risks during pregnancy
  • Presence in breast milk
  • Need to monitor breastfed infants for adverse effects

Precautions & Warnings

  • Weekly monitoring of complete blood counts
  • Ophthalmic evaluation for visual impairment symptoms
  • Not approved for catheter-related bloodstream infections
  • Risk of Clostridium difficile-associated Diarrhea (CDAD)
  • Monitoring for potential increases in blood pressure

Overdose Effects

  • No reported cases of overdose
  • Symptomatic and supportive care advised
  • Approximately 30% removal during 3 hours of haemodialysis

Therapeutic Class

  • Macrolides

Reconstitution

  • Shake bottle to loosen powder for oral suspension
  • Add specified amount of water to the dry mixture
  • Shake reconstituted suspension well before each use
  • Oral suspension should be used within 21 days after constitution

Storage Conditions

  • Store at room temperature (15°C-30°C)
  • Away from light and moisture
  • Keep away from children

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