Sinapol 120 mg/5 ml (Syrup)

100 ml bottle: ৳ 50.00

Medicine Details

Category Details
Generic Paracetamol
Company Ibn sina pharmaceuticals ltd
Also available as

Indications

  • Fever
  • Common cold
  • Influenza
  • Headache
  • Toothache
  • Earache
  • Bodyache
  • Myalgia
  • Neuralgia
  • Dysmenorrhoea
  • Sprains
  • Colic pain
  • Back pain
  • Post-operative pain
  • Postpartum pain
  • Inflammatory pain
  • Post vaccination pain in children
  • Rheumatic & osteoarthritic pain
  • Stiffness of joints

Pharmacology

  • Analgesic properties
  • Antipyretic properties
  • Weak anti-inflammatory activity
  • Action in the CNS
  • Increase in pain threshold
  • Inhibition of cyclooxygenase enzymes
  • Prostaglandin synthesis
  • Para aminophenol derivative

Dosage & Administration

  • Adult dosage: 1-2 tablets every 4 to 6 hours up to a maximum of 4 gm daily
  • Children (6-12 years) dosage: ½ to 1 tablet 3 to 4 times daily
  • Extended Release Tablet dosage for adults & children over 12 years
  • Syrup/Suspension dosage for different age groups
  • Suppository dosage for different age groups
  • Paediatric Drop dosage for different age groups
  • Tablet with actizorb technology dosage for adults and children
  • Special precaution for extended release tablet not to be crushed

Interaction

  • Diminished metabolization with barbiturates, tricyclic antidepressants and alcohol
  • Increased hepatotoxicity with alcohol
  • Induction of liver enzymes by anticonvulsants or oral steroid contraceptives

Contraindications

  • Known hypersensitivity to Paracetamol

Side Effects

  • Mild side effects
  • Haematological reactions
  • Thrombocytopenia
  • Leucopenia
  • Pancytopenia
  • Neutropenia
  • Agranulocytosis
  • Pancreatitis
  • Skin rashes
  • Allergic reactions

Pregnancy & Lactation

  • No ill effects in recommended dosage during pregnancy
  • Excretion in breast milk not clinically significant

Precautions & Warnings

  • Care advised in severe renal or hepatic impairment
  • Greater hazard of overdose in non-cirrhotic alcoholic liver disease
  • Advice against concurrent use of other Sinapol-containing products
  • Use only when clearly necessary

Overdose Effects

  • Possible liver damage in adults with 10 g or more intake
  • Potential liver damage with 5 g or more intake considering risk factors
  • Symptoms of overdose in the first 24 hours
  • Abnormalities of glucose metabolism
  • Metabolic acidosis
  • Hepatic failure leading to encephalopathy, haemorrhage, hypoglycaemia, and death
  • Acute renal failure with acute tubular necrosis
  • Immediate treatment essential
  • Consideration of activated charcoal if overdose within 1 hour
  • Measurement of plasma Paracetamol concentration
  • Use of N-acetylcysteine up to 24 hours post-ingestion

Therapeutic Class

  • Non opioid analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H9NO2
  • Chemical Structure image link

Common Questions about Sinapol 120 mg/5 ml Syrup

  • Action of Sinapol 120 mg/5 ml Syrup in obstructing the release of pain and fever chemical messengers
  • Uses for treatment and prevention of conditions and symptoms of diseases
  • Possible side effects
  • Storage and disposal instructions
  • Effective consumption with food or milk
  • Duration of use for improvement in conditions
  • No need to take more than recommended doses
  • Avoidance of OTC medications without consulting doctor or pharmacist
  • Use alongside antibiotics
  • Classification as a miscellaneous analgesic and not an NSAID drug
  • Quick tips for consumption including with food, avoidance of indigestion remedies, alcohol, and regular monitoring

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