Vogli 200 mcg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voglibose |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Title and Categories
- Vogli Tablets
- Anti-diabetic Medication
- Pharmacology
- Therapeutic Class: Alpha-Glucosidase Inhibitor
Indications
- Reduction in Post-Prandial Hyperglycaemia (PPHG)
- Immunotherapy for non-insulin-dependent diabetes mellitus (NIDDM) patients
- Combination therapy with other Oral Hypoglycaemic Agents (OHAs)
- Prevention of onset of type 2 diabetes mellitus in impaired glucose tolerance
- Use in glycogen storage disease
- Prevention of hypoglycaemia in non-diabetic Hyperinsulinemia
- Prevention of hypoglycaemic attacks in steroid-induced diabetes mellitus
Description
- Selectively inhibits α-glucosidase in the enteric canal
- Delays the digestion and absorption of carbohydrate
- Suppresses sharp increase in post-prandial plasma glucose
Mode of Action
- Inhibits membrane-bound intestinal alpha-glucosidases
- Blocks pancreatic alpha-amylase
- Reduces the rate of digestion of complex carbohydrates
- Decreases current blood glucose levels
- Small reduction in hemoglobin-A1c level
Dosage & Administration
- Orally administered in a single dose of 0.2 mg, 3 times a day
- Dose may be increased up to 0.3 mg if necessary
- Special caution in children and elderly patients
Interactions
- Careful administration when co-administered with antidiabetic drugs
- Drugs enhancing the hypoglycaemic action
- Drugs diminishing the hypoglycemic action
Contraindications
- Hypersensitivity to Voglibose or any excipients
- Diabetic ketoacidosis, diabetic pre-coma
- Severe infection, serious trauma
- Gastrointestinal obstruction or predisposition
Side Effects
- Diarrhoea, loose stools, abdominal pain
- Constipation, loss of appetite, nausea
- Vomiting, heartburn, increased gas
- Intestinal obstruction symptoms
Pregnancy & Lactation
- Safety not established in pregnancy
- Not recommended for lactating and nursing mothers
Precautions & Warnings
- Caution in patients receiving other antidiabetic drugs
- Careful administration in various pathological conditions
- Special attention in patients with hepatic or renal dysfunction
Use in Special Populations
- Poorly absorbed after oral doses
- Renal excretion is negligible
Overdose Effects
- Transient increase in flatulence
- Diarrhoea, abdominal discomfort
- No serious systemic reactions expected
Storage Conditions
- Keep in a cool and dry place
- Protect from light
- Keep out of the reach of children