Adorbis 5 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
Category | Details |
---|---|
Generic | Bisoprolol hemifumarate |
Company | Ziska pharmaceuticals ltd |
Also available as |
Product Title
Adorbis 5 mg Tablet
Categories
- Medicine
- Beta-blocker
- Anti adrenergic agent
- Therapeutic drug
Description
Adorbis 5 mg Tablet is indicated for treating hypertension, angina, and moderate to severe heart failure. It is a beta-blocker medication that works by blocking the effects of adrenaline to lower blood pressure, reduce the workload on the heart, and prevent chest pain.
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Pharmacology
- High affinity for ß1 adrenergic receptor
- Reduces heart rate and cardiac output
- Minimal impact on lipid metabolism
- High absorption and bioavailability
- Metabolized via oxidative pathways
- Balanced clearance between renal elimination and hepatic metabolism
- Elimination half-life of 10-12 hours
Dosage & Administration
- Adult dosage of 5 mg once daily, may be increased to 10 mg and then to 20 mg if necessary
- Dose titration interval of 2 weeks
- No established safety and effectiveness in children
- Caution in patients with renal or hepatic impairment
- No need for dose adjustment in the elderly unless significant renal or hepatic dysfunction is present
Interaction
- Not to be combined with other β-blocking agents
- Closely monitor patients receiving catecholamine-depleting drugs
- Caution with centrally active antihypertensive agents, antiarrhythmic agents, and calcium channel blockers
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side Effects
- Fatigue
- Dizziness
- Headache
- Disturbances of the gut (nausea, vomiting, diarrhea, constipation, abdominal pain)
- Cold or numb extremities (e.g. hands and feet)
- Muscle weakness or cramps
- Breathing difficulties due to bronchospasm in individuals with asthma or COPD
Pregnancy & Lactation
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
- Consideration for nursing mothers should involve stopping nursing if essential use of the drug is determined
Precautions & Warnings
- Use caution in adjusting the dose in patients with impaired renal or hepatic function
- Patients with a history of severe anaphylactic reaction may be more reactive to allergens
Therapeutic Class
Anti adrenergic agent (Beta blockers), Beta-adrenoceptor blocking drugs, Beta-blockers
Storage Conditions
Store in a dry place away from light and heat, keep out of reach of children
Chemical Structure
- Molecular Formula: C18H31NO4
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-135-bisoprolol-hemifumarate-chemical-structure-rpXCAgy2GIOFKWUs5Peu.svg
Common Questions
- What is Adorbis 5 mg Tablet?: A beta-blocker medication for lowering blood pressure, reducing the workload on the heart, and preventing chest pain
- What is Adorbis 5 mg Tablet used for?: High blood pressure, chest pain (angina), and heart failure
- How should I take Adorbis 5 mg Tablet?: Orally, with or without food, once daily at the same time each day
- What are the side effects of Adorbis 5 mg Tablet?: Dizziness, fatigue, headache, slow heart rate, difficulty breathing, cold hands and feet
- Is Adorbis 5 mg Tablet safe to take?: Generally safe, but consult a doctor if you have specific health conditions
- Should I use Adorbis 5 mg Tablet empty stomach, before food or after food?: After food in a prescribed dosage
- What are the instructions for the storage and disposal of Adorbis 5 mg Tablet?: Store in a cool dry place in its original packaging, away from children and pets