Zerotil plus (125 mg+31.25 mg)/5 ml (Powder for Suspension)

70 ml bottle: ৳ 285.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Beacon pharmaceuticals plc
Also available as
Zerotil plus 250 mg tablet Zerotil plus 500 mg tablet

Title

Zerotil Plus 125 Suspension

Categories

  • Medicine
  • Antibiotic
  • Cephalosporin

Description

Zerotil Plus 125 Suspension is indicated for the treatment of infections caused by sensitive bacteria. It is a bactericidal second generation cephalosporin antibiotic with a beta-lactamase inhibitor used to treat various bacterial infections.

Color options

  • White

Dimensions

  • Volume: 125 ml
  • Packaging dimensions: 10 x 5 x 5 cm

Functions

  • Bactericidal
  • Inhibits bacterial cell wall synthesis
  • Beta-lactamase inhibition

Materials

  • Cefuroxime
  • Clavulanic acid
  • Sucrose
  • Sorbitol
  • Microcrystalline cellulose
  • Xanthan gum
  • Sodium benzoate

Technical specifications

  • Bacterial susceptibility:
    • Gram-positive
    • Gram-negative
  • Age group:
    • Adolescents
    • Adults
    • Pediatric patients (3 months to 12 years)
  • Dosage form: Oral Suspension

Design elements

  • Suspension formulation
  • Flavored for better taste
  • Child-resistant cap

Usability features

  • No need to refrigerate
  • Easy to administer
  • Includes dosing cup or spoon

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort
  • Renal dysfunction (rare)

Pregnancy and lactation

Safe for later pregnancy, excreted into breast milk in small quantities

Precautions and warnings

  • Use with care in patients receiving potent diuretics
  • History of colitis

Storage conditions

Store below 30°C, away from light and moisture

Therapeutic class

Second generation Cephalosporins

Interaction

  • Increased area under the serum concentration with probenecid
  • Lower bioavailability with gastric acidity-reducing drugs

Dosage and administration

  • Adolescents and adults:
    • Pharyngitis tonsillitis: 250 mg b.i.d. for 5-10 days
    • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
    • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
    • Uncomplicated skin infections: 250-500 mg b.i.d. for 10 days
    • Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
    • Uncomplicated gonorrhoea: 1000 mg b.i.d. Single dose
  • Pediatric patients:
    • Pharyngitis tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
    • Acute otitis media: 30 mg/kg/day b.i.d for 10 days
    • Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
    • Impetigo: 30 mg/kg/day b.i.d for 10 days

Drug interaction

  • Probenecid increases serum concentration
  • Gastric acidity-reducing drugs lower bioavailability

Commonly asked questions

  • What is it: Cefuroxime is the cephalosporin antibiotic and Clavulanic acid is a beta-lactamase inhibitor. Zerotil plus 125 Syrup is indicated for the treatment of infections caused by sensitive bacteria.
  • Uses: Treats pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever
  • Onset of effect: Starts working within 2-3 hours
  • Duration of effect: Lasts for an average duration of 4-8 hours
  • Alcohol consumption: Interaction with alcohol is unknown, consult doctor
  • Habit forming: No habit-forming tendencies reported
  • Pregnancy and breastfeeding: Safe to use during pregnancy and breastfeeding with doctor consultation
  • Quick tips:
    • Complete the full course of treatment
    • Take with food to avoid upset stomach
    • Stop and inform doctor if itchy rash, swelling, or breathing difficulties occur

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