Epicet XR 1500 mg (Tablet (Extended Release))
Unit Price: ৳ 50.00 (3 x 4: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levetiracetam |
| Company | Renata limited |
| Also available as |
Title
- Epicet XR
Categories
- Anti-epileptic Drugs
- Adjunct Therapy
- Monotherapy
Description
The precise mechanism(s) by which Epicet XR exerts its antiepileptic effect is unknown. It inhibits burst firing without affecting normal neuronal excitability, suggesting that it may selectively prevent hyper synchronization of epileptiform burst firing and propagation of seizure activity.
Indications
- Treatment of partial-onset seizures
- Adjunctive therapy for myoclonic seizures
- Adjunctive therapy for primary generalized tonic-clonic seizures
Dosage
- Starting dose for adults and adolescents is 250 mg twice daily
- Initial therapeutic dose for adults (≥18 years) is 500 mg twice daily
- Maximum dose is 1500 mg twice daily
Administration
- Oral administration
- Should be taken with sufficient quantity of liquid
- Can be taken with or without food
Interaction
- No influence on serum concentrations of existing antiepileptic drugs
- Potential interaction with probenecid, methotrexate, and laxatives
- Absorption not altered by food, but rate of absorption slightly reduced
Contraindications
- Hypersensitivity to the active substance or other pyrrolidone derivatives or to any of the excipients
Side Effects
- Common adverse reactions include somnolence, asthenia, infection, dizziness, fatigue, aggression, nasal congestion, decreased appetite, and irritability
Pregnancy & Lactation
- Not recommended during pregnancy
- Excreted in human breast milk
- Breastfeeding not recommended unless clinically necessary
Precautions & Warnings
- Dose adjustments needed for patients with renal impairment
- Rare cases of decreased blood cell counts described
- Suicidal ideation and behaviours have been reported
- Tablet formulation not adapted for use in infants and children under the age of 6 years
Use in Special Populations
- Dose adjustment recommended for elderly patients with compromised renal function
- Daily dose must be individualized according to renal function for patients with renal impairment
- No dose adjustment needed in patients with mild to moderate hepatic impairment
Overdose Effects
- Symptomatic treatment may include haemodialysis
Therapeutic Class
- Adjunct anti-epileptic drugs
Storage Conditions
- Store at a temperature not exceeding 25°C, protected from light