Gavipres (500 mg+267 mg+160 mg)/10 ml (Oral Suspension)

200 ml bottle: ৳ 250.00

Medicine Details

Category Details
Generic Sodium alginate sodium bicarbonate calcium carbonate
Company Silva pharmaceuticals ltd

Indications

  • Gastric reflux
  • Heartburn
  • Indigestion
  • Flatulence associated with gastric reflux
  • Heartburn of pregnancy
  • Epigastric distress
  • Retrosternal distress

Pharmacology

  • Combination of two antacids (Calcium carbonate and Sodium bicarbonate) and an alginate (Sodium alginate)
  • Neutralizes excess stomach acid
  • Forms a protective barrier over the stomach contents
  • Physical mode of action
  • Rapid reaction with gastric acid
  • Forms a raft of Alginic Acid gel
  • Reduces esophageal acid exposure
  • Floats on the stomach contents
  • Impedes gastro-esophageal reflux
  • Protects the esophagus from Acid, Pepsin, and Bile
  • Entaps bile and pepsin within its structure
  • Raft may be refluxed into the esophagus
  • Demulcent effect
  • Increases relief from indigestion and heartburn

Dosage & Administration

  • Oral suspension for adults and children over 12 years
  • Oral suspension for children 6 to 12 years
  • Chewable Tablet for adults and children 12 years and over
  • Chewable Tablet for children under 12 years
  • Oral suspension dosage after meals and at bedtime
  • Chewable Tablet dosage after meals and at bedtime
  • Dosage not recommended for children under 6 years
  • No dose modifications necessary for elderly
  • Caution for highly restricted salt diet in renal insufficiency patients

Interaction

  • Time-interval of 2 hours between Gavipres intake and other medicinal products
  • Potential interactions with Tetracyclines, Digoxine, Fluoroquinolone, Iron salt, Ketoconazole, Neuroleptics, Thyroid Hormones, Penicillamine, beta-blockers, Glucocorticoid, Chloroquine, Biphosphonates, Estramustine

Contraindications

  • Hypersensitivity to active ingredients or excipients

Side Effects

  • Constipation
  • Flatulence
  • Stomach cramp
  • Belching
  • Sensation of swelling with high dose

Pregnancy & Lactation

  • No malformative nor feto/neonatal toxicity
  • Can be used during pregnancy if clinically needed
  • No effects on breastfed newborns/infants
  • No negative effect on parental or offspring fertility or reproduction

Precautions & Warnings

  • High sodium content (254.5 mg in 20 ml dose)
  • Care needed in treating patients with hypercalcaemia, nephrocalcinosis, and recurrent calcium containing renal calculi
  • Not generally recommended for children under 12 years except on medical advice
  • High in sodium, caution for highly restricted salt diet
  • Caution in patients with impaired renal function/insufficiency and hypophosphatemia

Overdose Effects

  • Symptomatic treatment for overdose
  • Abdominal distension may occur

Therapeutic Class

  • Antacids

Storage Conditions

  • Store in a cool and dry place (below 30°C)
  • Keep away from light
  • Do not refrigerate or freeze
  • Keep out of the reach of children

Common Questions about Gavipres 500 Suspension

  • Combination of two antacids and an alginate
  • Used to treat Gastric reflux, Heartburn, Indigestion, Flatulence associated with gastric reflux
  • Safe in pregnancy and breastfeeding

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