Pyra Plus 500 mg+65 mg (Tablet)
Unit Price: ৳ 2.00 (15 x 10: ৳ 300.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol caffeine |
| Company | Renata limited |
Title and Categories
- Paracetamol & Caffeine Tablets
- Medicine
- Non opioid analgesics
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
- Combination of Paracetamol and Caffeine
- Analgesic properties
- Antipyretic properties
- Weak anti-inflammatory activity
- Increased solubility and transmembrane permeation of Paracetamol
- Increased pain threshold and tolerance of pain
- Raises vessel tone in the brain
Dosage & Administration
- Adult dose: 1-2 tablets every 4-6 hours
- Maximum adult dose: 8 tablets daily
- Not recommended for children below 12 years
Interaction
- May reduce serum levels with anticonvulsants
- Enhance the anticoagulant effect of warfarin and other coumarins
- Accelerated absorption with metoclopramide and domperidone
- May increase serum levels with probenecid
- May increase serum levels of chloramphenicol
- May reduce absorption with colestyramine within 1 hour of admin
- May cause severe hypothermia with phenothiazine
Contraindications
- Severe renal function impairment
- Hepatic disease (Viral Hepatitis)
- Known hypersensitivity to paracetamol or caffeine
Side Effects
- Mild side effects of paracetamol
- Haematological reactions
- Thrombocytopenia
- Leukopenia
- Pancytopenia
- Neutropenia
- Agranulocytosis
- Pancreatitis
- Skin rashes
- Other allergic reactions
Pregnancy & Lactation
- Consultation required for pregnant mothers
- Can be taken while breastfeeding
Precautions & Warnings
- Cautious use in patients with hepatic or renal failure
- Cautious use in patients taking other hepatotoxic medication
- Avoid prolonged use without consulting a physician
Overdose Effects
- Symptoms of Paracetamol overdose in the first 24 hours
- Liver damage
- Abnormalities of glucose metabolism
- Metabolic acidosis
Storage Conditions
- Store in a cool and dry place
- Protect from light and moisture
- Keep out of the reach of children