Sitacret-M 50 mg+500 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin metformin hydrochloride |
| Company | Renata limited |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Not for type 1 diabetes treatment
- Improves glycemic control
Pharmacology
- Combines sitagliptin and metformin
- DPP-4 inhibitor and biguanide class
- Inhibits incretin hormones
- Regulates glucose homeostasis
Dosage & Administration
- Individualized dosage
- Twice daily with meals
- Gradual dose escalation
- Initial combination therapy
- Maintenance therapy
- Maximum recommended daily dose
Interaction
- Cationic drugs caution
- Phenprocoumon interaction
- Levothyroxine interaction
Contraindications
- Renal disease or dysfunction
- Metabolic acidosis
- Hypersensitivity reaction
- Radiologic studies with iodinated contrast materials
Side Effects
- Diarrhea
- Upper respiratory tract infection
- Headache
- Hypoglycemia
- Nasopharyngitis
- Nausea/vomiting
- Fatulence
Pregnancy & Lactation
- Pregnancy Category B
- Use during pregnancy if needed with caution
- Caution during nursing
Precautions & Warnings
- Lactic acidosis risk factors
- Thyroid-stimulating hormone monitoring
- Vitamin B12 level monitoring
- Hepatic disease caution
- Renal function assessment
- Pancreatitis risk monitoring
Overdose Effects
- Supportive measures for overdose
- Dialyzable property of sitagliptin and metformin
- Pancreatitis risk with metformin overdose
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Store below 25°C
- Dry place away from light
- Keep out of reach of children
- Do not use after expiry date