Clonaben 1 mg (Tablet)

Unit Price: ৳ 7.50 (5 x 10: ৳ 375.00)
Strip Price: ৳ 75.00

Medicine Details

Indications

  • Treatment of panic disorder
  • Treatment of Lennox-Gastaut Syndrome
  • Treatment of akinetic seizures
  • Treatment of myoclonic seizures
  • Treatment of absence seizures
  • Long-term use effectiveness

Pharmacology

  • Anticonvulsive effects
  • Sedative effects
  • Muscle relaxing effects
  • Anxiolytic effects
  • Enhancement of GABAergic neurotransmission
  • Positive allosteric modulation of GABA receptor
  • Effect on serotonin
  • Suppression of paroxysmal activity
  • Beneficial effects in generalized and focal epilepsies

Dosage & Administration

  • Initial dose for adults with seizure disorders
  • Maximum recommended daily dose for adults
  • Initial dose for adults with panic disorder
  • Initial dose for pediatric patients
  • Dosage adjustment for infants and children
  • Dosage for injection in infants, children, and adults

Interaction

  • Effects on the metabolism of phenytoin, carbamazepine, phenobarbital

Contraindications

  • Hypersensitivity to benzodiazepines
  • Significant liver disease
  • Open angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Coma
  • Tremor
  • Vertigo
  • Depression
  • Amnesia
  • Hallucinations
  • Insomnia
  • Palpitations

Pregnancy & Lactation

  • Potential for congenital malformations
  • Evidence of teratogenic effects
  • Compelling indication for administration during pregnancy
  • Adverse effects in the neonate
  • Recommendation to discontinue breastfeeding

Precautions & Warnings

  • Increased incidence of generalized tonic-clonic seizures
  • Concomitant use with valproic acid
  • Increased pharmacologic effects in elderly patients
  • Effects on renal impairment
  • Plasma protein binding in cirrhotic patients

Use in Special Populations

  • Increased production of saliva and bronchial secretion in infants and small children
  • Greater pharmacologic effects in elderly patients
  • Effect on renal impairment
  • Effect on hepatic impairment

Overdose Effects

  • Common symptoms
  • Life-threatening effects if taken with other CNS depressants
  • Symptomatic and supportive treatment
  • Use of flumazenil as a benzodiazepine antagonist

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Dilution for slow intravenous injection
  • Dilution for intravenous infusion
  • Stability of diluting media
  • Prevention of further absorption
  • Use of PVC infusion bags

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular formula
  • Chemical structure image

Common Questions

  • Use as a sleeping pill
  • Long-term use
  • Withdrawal symptoms
  • Early symptoms of suicidal thoughts
  • Effect on weight
  • Effect on memory
  • Harmful effects of higher doses
  • Combination with zolpidem
  • Combination with quetiapine
  • Quick Tips for usage

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