Lim 2.5 mg+500 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)

Strip Price: ৳ 120.00

Medicine Details

Category	Details
Generic	Linagliptin metformin hydrochloride
Company	Benham pharmaceuticals ltd
Also available as	Lim 25 mg tablet

Indications

Adjunct to diet and exercise
Improves glycemic control
Type 2 diabetes mellitus

Pharmacology

Inhibitor of DPP-4 enzyme
Increases concentrations of active incretin hormones
Stimulates insulin release from pancreatic beta cells
Decreases glucagon secretion from pancreatic alpha cells
Oral antihyperglycemic drug
Lowers plasma glucose levels
Improves insulin sensitivity

Dosage & Administration

Max recommended dose of 2.5 mg Linagliptin
Max recommended dose of 1000 mg Metformin Hydrochloride
Dose escalation should be gradual
Immediate release tablet
Extended release tablet
Individualized dosage based on effectiveness and tolerability

Interaction

Cationic Drugs interaction
Carbonic Anhydrase Inhibitors interaction
Inducers of P-glycoprotein and CYP3A4 Enzymes interaction
Drugs affecting glycemic control

Contraindications

Renal impairment
Acute or chronic metabolic acidosis
Hypersensitivity to Linagliptin or Metformin Hydrochloride

Side Effects

Nasopharyngitis
Diarrhea
Hypoglycemia

Pregnancy & Lactation

Use during pregnancy only if clearly needed
Caution during lactation

Precautions & Warnings

Discontinue in case of lactic acidosis or acute pancreatitis
Discontinue before radiologic studies
Monitor Vitamin B12 levels annually
Symptoms of lactic acidosis
Symptoms of pancreatitis
Alcohol precautions
Counseling recommendations
Travel recommendations
Emergency preparedness
Hypoglycemia precautions

Overdose Effects

Supportive treatment
Removal of unabsorbed material
Clinical monitoring
Dialyzable Metformin Hydrochloride
No dose-related clinical adverse drug reactions

Therapeutic Class

Oral hypoglycemic preparations

Storage Conditions

Cool & dry place
Below 30°C
Protected from light & moisture
Keep out of reach of children

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