Rabnil MUPS 20 mg (MUPS Tablet)

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)

Strip Price: ৳ 100.00

Medicine Details

Category	Details
Generic	Rabeprazole sodium
Company	Benham pharmaceuticals ltd
Also available as	Rabnil 20 mg capsule

Title and Categories

Rabnil MUPS 20 mg Gastro-resistant Tablet
Pharmaceuticals
Proton Pump Inhibitor

Indications

Treatment of active duodenal ulcer
Treatment of active benign gastric ulcer
Symptomatic treatment of erosive or ulcerative gastro-esophageal reflux disease (GERD)
Long-term management of gastro-esophageal reflux disease (GERD maintenance)
Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
Treatment of Zollinger-Ellison Syndrome
In combination with antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase

Dosage

Oral dose for active duodenal ulcer and active benign gastric ulcer is 20 mg once daily in the morning
Oral dose for erosive or ulcerative GERD is 20 mg once daily for four to eight weeks
Maintenance dose of rabeprazole sodium 20 mg or 10 mg once daily for long-term management
Treatment of Zollinger-Ellison Syndrome starting with 60 mg once a day, titrated upwards to 120 mg/day

Administration

Tablets should be taken in the morning before eating and swallowed whole

Interaction

Potential interaction with compounds whose absorption is pH dependent
Co-administration with ketoconazole or itraconazole may decrease antifungal plasma levels
No interaction with liquid antacids observed

Contraindications

Hypersensitivity to the active substance or excipients
Contra-indicated in pregnancy and during breastfeeding

Side Effects

Headache
Diarrhea
Abdominal pain
Vomiting
Constipation
Dry mouth
Changes in appetite
Muscle pain
Drowsiness
Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C', not recommended during breastfeeding

Precautions & Warnings

Symptomatic response does not exclude the presence of gastric or esophageal malignancy
Regular surveillance for long-term patients
Possibility of increased risk of hip, wrist, and spine fracture with long-term use, especially in the elderly
Hypomagnesaemia and vitamin B12 absorption concerns
Risk of cross-hypersensitivity reactions with other proton pump inhibitors
Monitoring for blood dyscrasias and hepatic enzyme abnormalities

Use in Special Populations

No dose adjustment for patients with renal or hepatic impairment
Not recommended for use in children due to lack of safety and efficacy data

Overdose Effects

Maximum established exposure up to 60 mg twice daily
Effects are generally minimal and reversible without further medical intervention
No specific antidote known, treatment should be symptomatic and supportive

Storage Conditions

Keep below 30°C temperature, away from light & moisture, out of the reach of children

Chemical Structure

Molecular Formula: C18H21N3O3S

Commonly Asked Questions

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Side effects related to bone problems
Co-administration with vitamin D
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