Rabnil MUPS 20 mg (MUPS Tablet)

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Rabeprazole sodium
Company Benham pharmaceuticals ltd
Also available as
Rabnil 20 mg capsule

Title and Categories

  • Rabnil MUPS 20 mg Gastro-resistant Tablet
  • Pharmaceuticals
  • Proton Pump Inhibitor

Indications

  • Treatment of active duodenal ulcer
  • Treatment of active benign gastric ulcer
  • Symptomatic treatment of erosive or ulcerative gastro-esophageal reflux disease (GERD)
  • Long-term management of gastro-esophageal reflux disease (GERD maintenance)
  • Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
  • Treatment of Zollinger-Ellison Syndrome
  • In combination with antibacterial therapeutic regimens for the eradication of Helicobacter pylori in patients with peptic ulcer disease

Pharmacology

  • Suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase

Dosage

  • Oral dose for active duodenal ulcer and active benign gastric ulcer is 20 mg once daily in the morning
  • Oral dose for erosive or ulcerative GERD is 20 mg once daily for four to eight weeks
  • Maintenance dose of rabeprazole sodium 20 mg or 10 mg once daily for long-term management
  • Treatment of Zollinger-Ellison Syndrome starting with 60 mg once a day, titrated upwards to 120 mg/day

Administration

Tablets should be taken in the morning before eating and swallowed whole

Interaction

  • Potential interaction with compounds whose absorption is pH dependent
  • Co-administration with ketoconazole or itraconazole may decrease antifungal plasma levels
  • No interaction with liquid antacids observed

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Contra-indicated in pregnancy and during breastfeeding

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Dry mouth
  • Changes in appetite
  • Muscle pain
  • Drowsiness
  • Dizziness

Pregnancy & Lactation

US FDA pregnancy category 'C', not recommended during breastfeeding

Precautions & Warnings

  • Symptomatic response does not exclude the presence of gastric or esophageal malignancy
  • Regular surveillance for long-term patients
  • Possibility of increased risk of hip, wrist, and spine fracture with long-term use, especially in the elderly
  • Hypomagnesaemia and vitamin B12 absorption concerns
  • Risk of cross-hypersensitivity reactions with other proton pump inhibitors
  • Monitoring for blood dyscrasias and hepatic enzyme abnormalities

Use in Special Populations

  • No dose adjustment for patients with renal or hepatic impairment
  • Not recommended for use in children due to lack of safety and efficacy data

Overdose Effects

  • Maximum established exposure up to 60 mg twice daily
  • Effects are generally minimal and reversible without further medical intervention
  • No specific antidote known, treatment should be symptomatic and supportive

Storage Conditions

Keep below 30°C temperature, away from light & moisture, out of the reach of children

Chemical Structure

Molecular Formula: C18H21N3O3S

Commonly Asked Questions

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  • Side effects related to bone problems
  • Co-administration with vitamin D
  • Quick Tips for usage

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