Trusert A 5 mg+40 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- Combination therapy for blood pressure control
Pharmacology
- Fixed dose combination of Telmisartan and Amiodipine
- Telmisartan blocks vasoconstrictor and aldosterone-secreting effects
- Amiodipine inhibits calcium ion influx into vascular smooth muscle
- Reduces peripheral vascular resistance and blood pressure
Dosage & Administration
- Initial therapy with 40/5 mg once daily
- Add-on therapy for inadequate blood pressure control
- Replacement therapy for amiodipine and telmisartan
- Maximum recommended dose is 80/10 mg once daily
Interactions
- No clinically significant interaction with several medications
- Possible inhibition of CYP2C19 metabolism
Contraindications
- Hypersensitivity to the product or its components
- Pregnancy and lactation
- Biliary obstructive disorders, severe hepatic impairment, hypotension, cardiogenic shock, left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Headache
- Hypotension
- Cough
- Abdominal pain
- Nausea
- Erectile dysfunction
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Unknown excretion in human milk
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion before therapy
- Monitor for hypotension
- Monitor for worsening heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
Use in Special Populations
- Not established for pediatric patients
- Not recommended in patients ≥75 years old
- Not recommended in hepatically impaired patients
Overdose Effects
- Manifestations of telmisartan overdose: hypotension, dizziness, tachycardia
- Manifestations of amiodipine overdose: excessive peripheral vasodilation, marked hypotension, reflex tachycardia
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children