Trusert A 5 mg+80 mg (Tablet)

Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00

Medicine Details

Title

  • Telmisartan and Amiodipine Combination Tablet

Category

  • Medicine
  • Antihypertensive

Indications

  • Treatment of hypertension
  • Initial therapy for achieving blood pressure goals

Pharmacology

  • Non-peptide angiotensin receptor blocker
  • Dihydropyridine calcium-channel blocker
  • Inhibition of calcium ion influx into vascular and cardiac muscle

Dosage & Administration

  • Initial starting dose of 40/5 mg once daily
  • Maximum recommended dose of 80/10 mg once daily
  • Add-on therapy for inadequate blood pressure control

Interaction

  • No clinically significant interaction with acetaminophen, glyburide, simvastatin, warfarin, or ibuprofen
  • Safe co-administration with thiazide diuretics, beta-blockers, ACE inhibitors, nitrates, digoxin, and oral hypoglycemic drugs

Contraindications

  • Hypersensitivity to the product or any of its components
  • Pregnancy and lactation
  • Biliary obstructive disorders
  • Severe hepatic impairment
  • Hypotension
  • Cardiogenic shock
  • Left ventricle outflow tract obstruction

Side Effects

  • Dizziness
  • Peripheral edema
  • Migraine
  • Headache
  • Bradycardia
  • Palpitations
  • Cough
  • Abdominal pain
  • Diarrhea
  • Nausea
  • Pruritus
  • Myalgia
  • Erectile dysfunction
  • Chest pain
  • Fatigue

Pregnancy & Lactation

  • Pregnancy Category C (first trimester) and D (second and third trimesters)
  • Unsure excretion in human milk
  • Recommendation to discontinue nursing if drug is essential for the mother

Precautions & Warnings

  • Avoid fetal or neonatal exposure
  • Correct any volume or salt depletion before initiating therapy
  • Monitor for signs and symptoms of hypotension
  • Titrate slowly in patients with hepatic or severe renal impairment
  • Monitor for worsening heart failure

Use in Special Populations

  • Pediatric use not established
  • Not recommended for patients over 75 years old
  • Not recommended for hepatically impaired patients

Overdose Effects

  • Manifestations of hypotension, dizziness, tachycardia, and bradycardia
  • Excessive peripheral vasodilation with marked hypotension and reflex tachycardia

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Protect from light and high humidity
  • Keep out of reach of children

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