Gemzen 1 gm/vial (IV Infusion)
1 gm vial: ৳ 5,500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Gemcitabine |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Non-Small Cell Lung Cancer
- Pancreatic Cancer
- Bladder Cancer
- Breast Cancer
- Ovarian Cancer
Pharmacology
- Metabolism by nucleoside kinases
- Inhibition of DNA synthesis
- Inhibition of ribonucleotide reductase
- Competes with dCTP for incorporation into DNA
- Induction of apoptosis
Dosage & Administration
- Recommended dose for different cancers
- Dosage reduction based on toxicity
- Intravenous infusion
- Cycle repetition
Interaction
- No confirmed interactions reported
- No specific drug interaction studies conducted
Contraindications
- Known hypersensitivity to Gemcitabine
Side Effects
- Haematological Toxicity
- Hepatic Toxicity
- Gastrointestinal effects
- Genito-Urinary Toxicity
- Pulmonary Toxicity
- Allergic Toxicity
- Neurotoxicity
- Alopecia
Pregnancy & Lactation
- Pregnancy Category D
- Unknown excretion in human breast milk
Precautions & Warnings
- Caution in patients with specific risks
- Schedule-dependent Toxicity
- Respiratory Failure
- Hemolytic Uremic Syndrome
- Radiation Therapy Toxicity
Use in Special Populations
- Elderly Patients
- Renal and Hepatic Impairment
- Limited data in children
Overdose Effects
- No known antidote
- Myelosuppression
- Paresthesias
- Severe rash
- Supportive therapy
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Store at 20°C to 25°C
- Away from light
- Do not refrigerate
- Keep out of the reach of children
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