Prelizer-HTZ 5 mg+6.25 mg (Tablet)

Unit Price: ৳ 10.00 (4 x 7: ৳ 280.00)

Strip Price: ৳ 70.00

Medicine Details

Category	Details
Generic	Bisoprolol fumarate hydrochlorothiazide
Company	Radiant pharmaceuticals ltd
Also available as	Prelizer htz 25 mg tablet

Indications

Treatment of Hypertension

Pharmacology

Additive antihypertensive effects
β1-selective adrenoceptor blocking agent
Benzothiadiazine diuretic

Dosage & Administration

Effective once-daily doses
Antihypertensive therapy initiation
Substitution for titrated individual components

Interaction

Potentiation of other antihypertensive agents
Cautious use with myocardial depressants
Increased risk of bradycardia with concomitant use of digitalis glycosides and beta-blockers

Contraindications

Cardiogenic shock
Overt cardiac failure
Second or third degree AV block
Marked sinus bradycardia
Anuria
Hypersensitivity to components or sulfonamide-derived drugs

Side Effects

Fatigue
Dizziness
Headache
Bradycardia
Arrhythmia
Peripheral ischemia
Chest pain
Palpitations
Cold extremities
Claudication
Orthostatic hypotension
Gastrointestinal disturbances

Pregnancy & Lactation

Pregnancy Category C
Use only if potential benefit justifies risk
Not studied in nursing mothers
Thiazides excreted in human breast milk

Precautions & Warnings

Potential hyperuricemia or acute gout
Warning signs of fluid and electrolyte imbalance
Risk of hypokalemia
Gradual withdrawal of therapy
Careful observation of patients

Overdose Effects

Bradycardia
Hypotension
Lethargy
Delirium
Coma
Convulsions
Respiratory arrest
Congestive heart failure
Bronchospasm
Hypoglycemia
Acute loss of fluid and electrolytes

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Keep below 30°C temperature
Away from light & moisture
Keep out of the reach of children

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