Cefaz 2 gm/vial (IV Injection)

2 gm vial: ৳ 300.00

Medicine Details

Category	Details
Generic	Ceftriaxone sodium
Company	Astra biopharmaceuticals ltd
Also available as	Cefaz 1 gm injection

Indications

Lower respiratory tract infections
Acute Bacterial Otitis Media
Skin and skin structure infections
Urinary tract infections
Gonorrhea
Bacterial Septicemia
Bone and joint infections
Meningitis
Prevention of postoperative infections
Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms.

Dosage

Adult: 1 to 2 gm by intravenous or intramuscular administration once a day
Pneumonia, Bronchitis, Acute bacterial otitis media, Skin and skin structure infection, Urinary tract infections, Bacterial Septicemia, Bone and joint infections, Meningitis: 1 to 2 g IV or IM once a day (or in equally divided doses twice a day); Maximum dose: 4 gm/day
Uncomplicated gonococcal infections: 250 mg IM as a single dose
Surgical prophylaxis: 1 g IV as a single dose 30 to 120 minutes before surgery
Infants and Children (01 month or older): 50 to 75 mg/kg intravenous or intramuscular administration once a day
Duration of therapy: 4 to 14 days; longer therapy may be required in complicated infections

Administration

Intramuscular Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Lidocaine HCI 1% injection
Intravenous Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Water for injection; 2 g Ceftriaxone in 20 ml of Water for injection
Injection Time: 2-4 minutes for intramuscular or intravenous injection; 30 minutes for tubing infusion
Preparation Stability: Solution maintains potency for at least 6 hours at room temperature or 24 hours at 5°C

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

Diarrhea
Nausea and vomiting
Stomatitis and glossitis
Rash
Pruritus
Urticaria
Edema
Erythema multiforme
Eosinophilia
Thrombocytopenia
Leucopenia
Anemia
Neutropenia
Elevations of SGOT or SGPT
Bilirubinemia
CNS reactions
Local phlebitis

Pregnancy & Lactation

Safety not established in pregnancy; caution advised during lactation

Precautions & Warnings

Risk of anaphylactic shock
Possible gallbladder sludge
Regular blood checks during prolonged treatment

Use in Special Populations

Must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

No specific antidote; treatment should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture; Keep out of the reach of children