Ceroclav 500 mg+125 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Cefuroxime axetil clavulanic acid |
Company | Astra biopharmaceuticals ltd |
Also available as |
Title
Ceroclav 500 mg Tablet
Categories
- Antibiotics
- Medication
- Pharmaceutical
Description
Cefuroxime-Clavulanic Acid Tablet used for the treatment of various bacterial infections.
DosageForm
Tablet
Strength
500 mg
Manufacturer
Not specified
Indications
- Pharyngitis/Tonsillitis
- Acute Bacterial Otitis Media
- Acute bacterial maxillary sinusitis
- Lower respiratory tract infections
- Uncomplicated skin and skin-structure infections
- Uncomplicated urinary tract infections
- Bone and Joint Infections
- Uncomplicated Gonorrhoea
- Early Lyme Disease (erythema migrans)
- Septicemia
- Meningitis
- Switch therapy (Injectable to oral)
Pharmacology
Cefuroxime inhibits bacterial cell wall synthesis; Clavulanic acid protects Cefuroxime from degradation by beta-lactamase enzymes and provides a solution for the treatment of bacterial infections caused by beta-lactam resistant bacteria.
DosageAndAdministration
- AdolescentsAndAdults:
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
- Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
- Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
- Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
- MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
- Early Lyme disease: 500 mg b.i.d. for 20 days
- PaediatricPatients:
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days
- AdministrationNotes: Tablet may be taken without regard of food
Interaction
Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%. Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime.
Contraindications
Contraindicated in patients with known allergy to cephalosporin & in patients with Pseudomembranous Colitis
SideEffects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort or pain
- Renal dysfunction (Rare)
- Anaphylaxis (Rare)
- Angioedema (Rare)
- Pruritis (Rare)
- Rash (Rare)
- Serum sickness like urticaria (Rare)
PregnancyAndLactation
Avoid in the first trimester, can be used in later pregnancy to treat infections, excreted into breast milk in small quantities
PrecautionsAndWarnings
Given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.
TherapeuticClass
Second generation Cephalosporins
StorageConditions
Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.
FAQs
- WhatIsIt: Cefuroxime is the cephalosporin antibiotic and Clavulanic acid is a beta-lactamase inhibitor. Ceroclav 500 mg Tablet is indicated for the treatment of infections caused by sensitive bacteria.
- CommonUses: Used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever.
- TimeToTakeEffect: Starts working within 2-3 hours after taking it.
- DurationOfEffect: Lasts for an average duration of 4-8 hours.
- AlcoholInteraction: Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- HabitForming: No habit-forming tendencies reported.
- PregnancySafety: Safe to use during pregnancy to treat bacterial infections.
- BreastfeedingSafety: Safe to use during breastfeeding. Enters into breast milk at low levels.
- QuickTips:
- Prescribed to treat bacterial infections, even if they have developed resistance.
- Do not skip any doses and finish the full course of treatment.
- Take it with food to avoid an upset stomach.
- Diarrhea may occur as a side effect; probiotics may help.
- Stop taking and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties
- Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.
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