Ceroclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)
70 ml bottle: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil clavulanic acid |
| Company | Astra biopharmaceuticals ltd |
| Also available as |
Title
- Ceroclav 125 Syrup
Categories
- Medicine
- Antibiotic
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis
- Acute Bacterial Otitis Media
- Acute bacterial maxillary sinusitis
- Lower respiratory tract infections
- Acute bacterial exacerbation of chronic bronchitis
- Uncomplicated skin and skin-structure infections
- Uncomplicated urinary tract infections
- Bone and Joint Infections
- Uncomplicated Gonorrhoea
- Early Lyme Disease
- Septicemia
- Meningitis
- Switch therapy (Injectable to oral)
Pharmacology
- Cefuroxime is a bactericidal second generation cephalosporin antibiotic
- Active against a wide range of Gram-positive and Gram-negative susceptible organisms
- Inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
- Clavulanic acid is a naturally derived beta lactamase inhibitor produced by Streptomyces clavuligerus
- Gives protection of Cefuroxime from degradation by beta lactamase enzymes
Dosage & Administration
- Adolescents and adults dosages for different infections
- Paediatric Patients dosages for different infections
- Cefuroxime-Clavulanic Acid tablet may be taken without regard of food
Interaction
- Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%
- Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime
Contraindications
- Cefuroxime-Clavulanic Acid is contraindicated in patients with known allergy to cephalosporin
- Contraindicated in patients with Pseudomembranous Colitis
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort or pain
- Prolonged administration may result in overgrowth of nonsusceptible microorganisms
- Rarely (<0.2%) renal dysfunction, anaphylaxis, angioedema, pruritis, rash and serum sickness like urticaria may appear
Pregnancy & Lactation
- Cefuroxime-Clavulanic Acid can be safely used in later pregnancy to treat urinary and other infections
- Excreted into the breast milk in small quantities, possibility of sensitizing the infant should be kept in mind
Precautions & Warnings
- Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics
- Given with care to patients who have history of colitis
Therapeutic Class
- Second generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30o C)
- Away from light and moisture
- Keep out of the reach of children
Common Questions about Ceroclav 125 Suspension
- Ceroclav 125 Syrup is indicated for the treatment of infections caused by sensitive bacteria
- Used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever
- Takes effect within 2-3 hours after taking it
- Effect lasts for an average duration of 4-8 hours
- Interaction with alcohol is unknown
- No habit-forming tendencies were reported for Ceroclav 125 Syrup
- Safe to use during pregnancy and breastfeeding
- Quick Tips for usage