Ceroclav (125 mg+31.25 mg)/5 ml (Powder for Suspension)

70 ml bottle: ৳ 250.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Astra biopharmaceuticals ltd
Also available as
Ceroclav 250 mg tablet Ceroclav 500 mg tablet

Title

  • Ceroclav 125 Syrup

Categories

  • Medicine
  • Antibiotic

Indications

  • Treatment of infections caused by sensitive bacteria
  • Pharyngitis/Tonsillitis
  • Acute Bacterial Otitis Media
  • Acute bacterial maxillary sinusitis
  • Lower respiratory tract infections
  • Acute bacterial exacerbation of chronic bronchitis
  • Uncomplicated skin and skin-structure infections
  • Uncomplicated urinary tract infections
  • Bone and Joint Infections
  • Uncomplicated Gonorrhoea
  • Early Lyme Disease
  • Septicemia
  • Meningitis
  • Switch therapy (Injectable to oral)

Pharmacology

  • Cefuroxime is a bactericidal second generation cephalosporin antibiotic
  • Active against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibits bacterial cell wall synthesis by interfering with the transpeptidation process
  • Clavulanic acid is a naturally derived beta lactamase inhibitor produced by Streptomyces clavuligerus
  • Gives protection of Cefuroxime from degradation by beta lactamase enzymes

Dosage & Administration

  • Adolescents and adults dosages for different infections
  • Paediatric Patients dosages for different infections
  • Cefuroxime-Clavulanic Acid tablet may be taken without regard of food

Interaction

  • Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%
  • Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime

Contraindications

  • Cefuroxime-Clavulanic Acid is contraindicated in patients with known allergy to cephalosporin
  • Contraindicated in patients with Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Prolonged administration may result in overgrowth of nonsusceptible microorganisms
  • Rarely (<0.2%) renal dysfunction, anaphylaxis, angioedema, pruritis, rash and serum sickness like urticaria may appear

Pregnancy & Lactation

  • Cefuroxime-Clavulanic Acid can be safely used in later pregnancy to treat urinary and other infections
  • Excreted into the breast milk in small quantities, possibility of sensitizing the infant should be kept in mind

Precautions & Warnings

  • Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics
  • Given with care to patients who have history of colitis

Therapeutic Class

  • Second generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30o C)
  • Away from light and moisture
  • Keep out of the reach of children

Common Questions about Ceroclav 125 Suspension

  • Ceroclav 125 Syrup is indicated for the treatment of infections caused by sensitive bacteria
  • Used to treat pharyngitis, tonsillitis, sinusitis, bronchitis, SSTI, UTI, gonorrhoea, pneumonia, typhoid fever
  • Takes effect within 2-3 hours after taking it
  • Effect lasts for an average duration of 4-8 hours
  • Interaction with alcohol is unknown
  • No habit-forming tendencies were reported for Ceroclav 125 Syrup
  • Safe to use during pregnancy and breastfeeding
  • Quick Tips for usage

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