T Cort 0.05% (Cream)

10 gm tube: ৳ 90.00

Medicine Details

Indications

  • Relief of inflammatory manifestations
  • Relief of pruritic manifestations
  • Treatment of corticosteroid responsive eczema/dermatitis

Pharmacology

  • High topical anti-inflammatory potency
  • Low HPA-axis suppressive activity
  • High degree of selectivity for the glucocorticoid receptor
  • Weak affinity for the progesterone receptor
  • Therapeutic potency related to half-life of the glucocorticoid-receptor complex

Dosage & Administration

  • Cream application: once daily
  • Ointment application: twice daily

Interaction

  • No known interactions

Contraindications

  • Rosacea
  • Acne vulgaris
  • Perioral dermatitis
  • Primary cutaneous viral infections
  • Hypersensitivity to any of the ingredients
  • Perianal and genital pruritus
  • Not indicated for use in children under one year of age

Side Effects

  • Local burning
  • Pruritus
  • Atrophic changes in the skin
  • Hypertrichosis
  • Hypopigmentation
  • Secondary infection
  • Allergic contact dermatitis
  • Exacerbation of dermatoses
  • Systemic absorption effects
  • Potential effects in infants and children

Pregnancy & Lactation

  • Consideration during pregnancy if benefits outweigh risks
  • Potential low excretion into breast milk
  • Weighing therapeutic benefits against potential hazards for breastfeeding mothers and babies

Precautions & Warnings

  • Low systemic absorption
  • Prolonged application to large areas may lead to adrenal suppression
  • Children may be more susceptible to systemic toxicity
  • Potential atrophic changes when treating severe eczema
  • Use of antimicrobial therapy for infected lesions
  • Cleansing before applying fresh dressing
  • Adverse effects of occlusive dressings

Overdose Effects

  • Acute overdosage is unlikely
  • Features of hypercorticism in case of chronic overdosage or misuse
  • Extremely low oral bioavailability

Therapeutic Class

  • Fluticasone & combined preparations topical

Storage Conditions

  • Store below 30°C
  • Do not freeze

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