G-Cox 90 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Etoricoxib
Company Gaco pharmaceuticals ltd
Also available as
G cox 120 mg tablet

Title and Categories

  • G-Cox 90mg Tablet
  • Pain Relief
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Symptomatic Relief

  • Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Inhibition of COX-2 reduces pain, inflammation, and fever with decreased potential for GI toxicity and effects on platelet aggregation
  • Dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150 mg daily

Dosage & Administration

  • 30 mg once daily for Osteoarthritis
  • 90 mg once daily for Rheumatoid arthritis and Ankylosing spondylitis
  • 120 mg once daily for Acute gouty arthritis
  • 90 mg once daily for Postoperative dental surgery pain, limited to a maximum of 3 days
  • Patients may require additional postoperative analgesia
  • Shortest duration and lowest effective daily dose should be used to minimize cardiovascular risks
  • Periodic re-evaluation of patient's need for relief and response to therapy

Medicine Interaction

  • Increase in prothrombin time with oral anticoagulants
  • Reduced effect of diuretics and antihypertensive drugs
  • Concomitant use with low-dose acetylsalicylic acid for cardiovascular prophylaxis
  • Possible increase in nephrotoxic effect of ciclosporin or tacrolimus
  • Decreased lithium renal excretion leading to increased lithium plasma levels

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or GI bleeding
  • History of bronchospasm, acute rhinitis, nasal polyps, allergic-type reactions to acetylsalicylic acid or NSAIDs including COX-2 inhibitors
  • Pregnancy and lactation
  • Severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min
  • Children and adolescents under 16 years of age
  • Inflammatory bowel disease
  • Congestive heart failure (NYHA ll-IV)
  • Uncontrolled hypertension, established ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Atrial fibrillation
  • Transient ischemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia and arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not recommended for use during breastfeeding

Precautions & Warnings

  • Caution with patients at risk of GI complications, elderly, concurrent use of NSAIDs or acetylsalicylic acid, or prior history of gastrointestinal disease
  • Careful consideration for patients with significant risk factors for cardiovascular events
  • Potential reduction in prostaglandin formation and renal blood flow leading to impaired renal function
  • Caution in patients with history of cardiac failure, left ventricular dysfunction, hypertension, or pre-existing edema
  • Monitoring of renal and liver function, discontinuation at first sign of hypersensitivity, caution with warfarin or other anticoagulants

Overdose Effects

  • Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
  • Usual supportive measures in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure Image: (Link to image)

Commonly Asked Questions

  • What is G-Cox 90 mg Tablet?
  • What are the uses of G-Cox 90 mg Tablet?
  • Duration of effect of G-Cox 90 mg Tablet
  • Onset of action of G-Cox 90 mg Tablet
  • Pregnancy warnings of G-Cox 90 mg Tablet
  • Habit forming tendencies
  • Breastfeeding warnings
  • Safety with alcohol
  • Safety to drive while on this medicine
  • Effect on kidney function
  • Effect on liver function
  • Quick tips for usage

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