G-Cox 120 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Etoricoxib
Company Gaco pharmaceuticals ltd
Also available as
G cox 90 mg tablet

Title and Category

  • G-Cox 120 mg Tablet
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Indications

  • Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Symptomatic Relief Dosage

  • 30 mg once daily for OA
  • 90 mg once daily for RA and Ankylosing spondylitis
  • 120 mg once daily for acute gouty arthritis
  • 90 mg once daily for postoperative dental surgery pain

Usage

  • Limited to a maximum of 3 days for postoperative dental surgery pain
  • Shortest duration possible and lowest effective daily dose should be used

Pharmacology

  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Decreases clinical signs and symptoms with decreased potential for gastrointestinal (GI) toxicity
  • Produces dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150 mg daily

Interactions

  • Increase in prothrombin time with oral anticoagulants
  • Reduction of the effect of diuretics and other antihypertensive drugs with NSAIDs
  • Safe concomitant use with low-dose acetylsalicylic acid for cardiovascular prophylaxis

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active gastrointestinal (GI) bleeding
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min

Side-effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Dry mouth
  • Taste disturbance
  • Anxiety
  • Myalgia and arthralgia
  • Confusion and hallucinations (very rarely)

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Excreted in the milk of lactating rats
  • Must not breastfeed

Precautions & Warnings

  • Caution with patients at risk of gastrointestinal complications with NSAIDs
  • Consideration for patients with significant risk factors for cardiovascular events
  • Monitoring of renal function in patients with reduced prostaglandin formation
  • Caution in patients with symptoms and/or signs suggesting liver dysfunction
  • Discontinue at the first appearance of skin rash or hypersensitivity

Overdose Effects

  • Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity

Storage Conditions

  • Store at a temperature below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

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