Prelica 150 mg (Capsule)

Unit Price: ৳ 35.11 (3 x 6: ৳ 631.98)
Strip Price: ৳ 210.66

Medicine Details

Category Details
Generic Pregabalin
Company Radiant pharmaceuticals ltd
Also available as
Prelica 50 mg capsule Prelica 75 mg capsule Prelica 25 mg capsule Prelica cr 825 mg tablet Prelica cr 165 mg tablet

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)

Maximum Recommended Dosage

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN): 300 mg/day
  • Postherpetic neuralgia (PHN): 300 mg/day
  • Fibromyalgia: 450 mg/day
  • Neuropathic pain associated with spinal cord injury: 600 mg/day

Administration

  • Route: Oral
  • Special Instructions: Pregabalin CR tablet should be administered after an evening meal

Storage Conditions

Below 30°C, protected from light & moisture, keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention

Contraindications

Known hypersensitivity to Pregabalin or any of its components

Pregnancy & Lactation

  • Pregnancy: Potential risk to a fetus, no adequate and well-controlled studies
  • Lactation: Small amounts detected in the milk, not recommended

Precautions & Warnings

  • Angioedema may occur and require immediate discontinuation
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur with concomitant CNS depressants
  • May cause dizziness and somnolence, impairing ability to drive or operate machinery
  • Withdrawal should be gradual over a minimum of 1 week

Overdose Effects

Reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, heart block

Drug Interactions

Unlikely to be involved in significant pharmacokinetic drug interactions

Pediatric Uses

  • Note: Safety and effectiveness have not been established in pediatric patients for several indications

Mode of Action

Binds with high affinity to the alpha2-delta site in central nervous system tissues

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Interaction with Food

Not applicable

Dosage Conversion

  • Pregabalin Tablet Total Daily Dose:
      • 75 mg/daily: 82.5 mg/day
      • 150 mg/daily: 165 mg/day
      • 225 mg/daily: 247.5 mg/day
      • 300 mg/daily: 330 mg/day
      • 450 mg/daily: 495 mg/day
      • 600 mg/daily: 660 mg/day

Use Frequency

As prescribed by the doctor

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