Prelica CR 82.5 mg (Tablet (Controlled Release))
Unit Price: ৳ 25.00 (5 x 6: ৳ 750.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) for DPN
- Recommended dose of Pregabalin is 75 to 150 mg two times a day or 50 to 100 mg three times a day for PHN
- Recommended dose of Pregabalin is 300 to 450 mg/day for fibromyalgia
- Recommended dose range of Pregabalin is 150 to 600 mg/day for spinal cord injury
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Swallowed whole and should not be split, crushed or chewed
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Most common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, thinking abnormal
- Most common side effects in pediatric patients for the treatment of partial onset seizures: increased weight, increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding not recommended during treatment
Precautions & Warnings
- Angioedema can occur and may be associated with life threatening respiratory compromise
- Discontinue immediately in case of hypersensitivity reactions
- Increase in risk of suicidal thoughts or behavior
- May cause dizziness and somnolence, impairing ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
- May cause peripheral edema
- Caution should be exercised when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness in pediatric patients have not been established
- Safety and effectiveness of extended-release tablet in pediatric patients have not been established
Overdose Effects
- Signs and symptoms: reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, heart block
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions about Prelica CR 82.5 mg Tablet
- Considered first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia
- To be taken till improvement in health conditions
- Should be taken in prescribed dosage after food
- Should be kept in cool dry place in its original packaging, unreachable to children and pets
- Works in different ways for different diseases