Lizid 400 mg (Tablet)

Unit Price: ৳ 60.00 (2 x 10: ৳ 1,200.00)
Strip Price: ৳ 600.00

Medicine Details

Category Details
Generic Linezolid
Company Radiant pharmaceuticals ltd
Also available as
Lizid 600 mg tablet

Indications

  • Treatment of Nosocomial pneumonia
  • Treatment of Community-acquired pneumonia
  • Treatment of Complicated skin and skin structure infection
  • Treatment of Uncomplicated skin and skin structure infections
  • Treatment of Vancomycin-resistant Enterococcus faecium infections

Pharmacology

  • Synthetic antibacterial agent
  • Belongs to oxazolidinones class
  • In vitro activity against Gram positive aerobic bacteria
  • In vitro activity against Gram positive anaerobic bacteria
  • In vitro activity against certain Gram negative bacteria

Dosage & Administration

  • Oral route administration
  • IV infusion administration
  • Dosage varies based on infection type
  • Dosage for pediatric patients
  • Dosage for adults and adolescents
  • Recommended duration of treatment
  • No dose adjustment necessary between IV and oral administration

Interaction

  • Reversible inhibitor of monoamine oxidase
  • Potential interactions with adrenergic and serotonergic agents
  • Enhancement of pressor response possible
  • Avoid high tyramine content foods while taking

Contraindications

  • Contraindicated in patients with hypersensitivity to Linezolid
  • Contraindicated in patients taking MAO inhibitors
  • Contraindicated in patients with uncontrolled hypertension
  • Contraindicated in patients with specific medical conditions

Side Effects

  • Most adverse events reported were mild to moderate
  • Common side effects include diarrhea, headache, and nausea
  • Other side effects include oral/vaginal moniliasis, hypertension, etc.

Pregnancy & Lactation

  • Use during pregnancy if benefit justifies risk
  • Consideration needed for breastfeeding mothers
  • Monitor breastfed infant for adverse effects

Precautions & Warnings

  • Monitor blood counts in patients on long-term treatment
  • Ophthalmic evaluation recommended for visual impairment symptoms
  • Not approved for catheter-related infections
  • C. difficile-associated Diarrhea risk
  • Monitoring required for potential blood pressure increases

Overdose Effects

  • No reported cases of overdose
  • Symptomatic and supportive care advised
  • Approximately 30% of dose removed during haemodialysis
  • No data for peritoneal dialysis or haemoperfusion

Therapeutic Class

  • Belongs to Macrolides class

Reconstitution

  • Shake bottle for oral suspension reconstitution
  • Add boiled and cooled water to dry mixture
  • Shake well after each addition
  • Intravenous administration instructions for ready-to-use infusion bottles

Storage Conditions

  • Store at room temperature away from light and moisture
  • Keep away from children

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