Lizid 600 mg (Tablet)

Unit Price: ৳ 85.00 (2 x 10: ৳ 1,700.00)

Strip Price: ৳ 850.00

Medicine Details

Category	Details
Generic	Linezolid
Company	Radiant pharmaceuticals ltd
Also available as	Lizid 400 mg tablet

Indications

Nosocomial pneumonia
Community-acquired pneumonia
Complicated skin and skin structure infections including diabetic foot infections
Uncomplicated skin and skin structure infections
Vancomycin-resistant Enterococcus faecium infections

Pharmacology

Synthetic antibacterial agent belonging to a new class of antibiotics with in vitro activity against Gram positive aerobic bacteria, some Gram positive anaerobic bacteria, and certain Gram negative bacteria.

Dosage & Administration

Infection:
- Nosocomial pneumonia
- Community-acquired pneumonia including concurrent bacteremia
- Complicated skin and skin structure infections
- Uncomplicated skin and skin structure infections
Dosage & Frequency:
- Pediatric patients: 10 mg/kg orally or intravenously every 8 hours
- Adults and adolescents: 600 mg orally or intravenously every 12 hours
Duration of Treatment:
- 10 to 14 days for nosocomial pneumonia and 14 to 28 days for complicated skin and skin structure infections

Interaction

Drug interaction with medication: Reversible, nonselective inhibitor of monoamine oxidase. Potential for interaction with adrenergic and serotonergic agents.
Drug interaction with food and others: Advice patients to avoid large quantities of foods or beverages with high tyramine content while taking Lizid.

Contraindications

Contraindicated for patients with known hypersensitivity to Linezolid or any of the other product components.

Side Effects

Diarrhea
Headache
Nausea
Oral moniliasis
Vaginal moniliasis
Hypertension
Dyspepsia
Localized abdominal pain
Pruritus
Tongue discoloration

Pregnancy & Lactation

Pregnancy: Use during pregnancy only if potential benefit justifies potential risk to the fetus.
Lactation: Linezolid is present in breast milk. Consider developmental and health benefits of breastfeeding along with the mother’s clinical need for linezolid.

Precautions & Warnings

Monitor complete blood counts weekly in patients receiving Lizid for longer than two weeks
Prompt ophthalmic evaluation if symptoms of visual impairment occur
Not approved for catheter-related bloodstream infections
Monitor for potential increases in blood pressure
Immediate medical evaluation for recurrent nausea or vomiting, unexplained acidosis, or low bicarbonate level

Overdose Effects

No reported cases of overdose. Symptomatic and supportive care is advised.

Therapeutic Class

Macrolides

Reconstitution

Oral Suspension: Shake the bottle to loosen powder. Add boiled and cooled water to the dry mixture in the bottle. Shake well before use. Store reconstituted suspension in a cool and dry place and use within 21 days.
Intravenous Administration: Administer by intravenous infusion over a period of 30 to 120 minutes. Store at room temperature.

Storage Conditions

Store at room temperature (15-30°C), away from light and moisture.