X-Pro 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.50 (3 x 10: ৳ 255.00)
Strip Price: ৳ 85.00

Medicine Details

Category Details
Generic Esomeprazole
Company Ambee pharmaceuticals ltd
Also available as
X pro 20 mg capsule

Product Title

  • X-Pro 40mg Capsule

Categories

  • Medicine
  • Pharmaceutical
  • Gastrointestinal Health

Description

  • Proton pump inhibitor for relief from chronic heartburn and GERD symptoms
  • Indicated for healing of erosive esophagitis and maintenance of healing
  • Used in combination therapy for Helicobacter pylori eradication
  • Treatment for Zollinger-Ellison Syndrome, Acid-related Dyspepsia, and Duodenal & Gastric ulcers

Color Options

  • N/A

Dimensions

  • N/A

Functions

  • Reduces gastric acid secretion
  • Relieves symptoms of heartburn and GERD
  • Promotes healing of esophageal erosions
  • Eradicates Helicobacter pylori infection
  • Treats Zollinger-Ellison Syndrome and various ulcers

Materials

  • Esomeprazole magnesium for oral dosage form
  • Enteric-coated pellet formulation for esomeprazole capsules

Technical Specifications

  • Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Systemic bioavailability is approximately 90%
  • 97% plasma protein binding
  • Extensively metabolized in the liver by the CYP enzyme system
  • Plasma elimination half-life is approximately 1-1.5 hours

Design Elements

  • Tablet or capsule to be swallowed whole
  • Oral suspension to be taken with water or administered through a tube
  • IV injection or infusion for specific conditions

Usability Features

  • Should be taken at least one hour before meals
  • Special administration technique for patients with difficulty swallowing capsules
  • Safe for use with antacids

Dosage Options

  • 20mg or 40mg doses for various conditions
  • Dosage adjustments for pediatric patients based on body weight
  • Different dosages for adult and pediatric patients for IV administration

Interaction

  • Extensively metabolized by CYP2C19 and CYP3A4
  • Potential interference with absorption of drugs influenced by gastric pH
  • Limited clinically significant interactions with other drugs

Indications

  • Relief from chronic heartburn and GERD symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome, Acid-related Dyspepsia, and various ulcers

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied, breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not preclude gastric malignancy
  • Special information for patients regarding capsule administration and antacid use

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed in the elderly
  • Dosage adjustment for severe hepatic insufficiency

Overdose Effects

  • Lethal dose observed in rats at a very high level
  • No specific antidote known, treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

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