Spilac-F 40 mg+50 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Essential hypertension
  • Chronic congestive heart failure
  • Hepatic cirrhosis
  • Swelling due to excess fluid retention
  • Hyperaldosteronism

Pharmacology

  • Complementary mechanisms
  • Additive diuretic effect
  • Sites of action
  • Na+/K+/2Cl- co-transporter inhibition
  • Aldosterone antagonism

Dosage and administration

  • Furosemide 20mg and spironolactone 50mg
  • Furosemide 40mg and spironolactone 50mg
  • Dosage for children and elderly

Interaction

  • ACE inhibitors interaction
  • Potassium salts interaction
  • Corticosteroids interaction
  • NSAIDs interaction
  • Aminoglycoside antibiotics interaction

Contraindications

  • Anuria
  • Acute renal insufficiency
  • Hyperkalaemia
  • Addison's disease
  • Sulphonamides hypersensitivity

Side effects

  • Headache
  • Drowsiness
  • Gastrointestinal distress
  • Ataxia
  • Gynaecomastia

Pregnancy and lactation

  • Spironolactone crossing placental barrier
  • Fetal abnormalities
  • Excretion in breast milk

Precautions and warnings

  • Electrolyte deficiency caution
  • Diabetes caution
  • Enlarged prostate caution
  • Hypotension caution

Therapeutic class

  • Potassium-sparing diuretics
  • Aldosterone antagonists

Storage conditions

  • Temperature below 30°C
  • Protection from light and moisture
  • Keep out of the reach of children

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