M-K 10 mg (Tablet)

Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00

Medicine Details

Category Details
Generic Montelukast sodium
Company Cosmo pharma laboratories ltd

Indications

  • Prophylaxis and chronic treatment of asthma
  • Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
  • Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis

Pharmacology

  • Leukotriene receptor antagonist
  • Inhibits the cysteinyl leukotriene receptor (CysLT1)
  • Correlated with the pathophysiology of asthma & allergic rhinitis

Dosage & Administration

  • Dosage for adults and adolescents 15 years of age and older: Montelukast 10 mg tablet once daily
  • Dosage for pediatric patients 6 to 14 years of age: Montelukast 5 mg tablet once daily
  • Dosage for pediatric patients 2 years to 5 years of age: Montelukast 4 mg tablet once daily
  • Dosage for pediatric patients 6 months to 5 years of age: Montelukast 4 mg oral granules once daily
  • No dosage adjustment required in patients with mild-to-moderate hepatic insufficiency
  • No dosage adjustment recommended in patients with renal insufficiency
  • Elderly use: No dosage adjustment required

Interaction

  • No clinically important effects on the pharmacokinetics of several drugs
  • Used concomitantly with a wide range of commonly prescribed drugs
  • Phenobarbital decreased the AUC of M-K approximately 40%

Contraindications

  • Patients who are hypersensitive to any component of this product

Side Effects

  • Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
  • Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
  • Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor

Pregnancy & Lactation

  • Use during pregnancy only if clearly needed
  • Caution should be exercised when given to a nursing mother

Precautions & Warnings

  • Not indicated for use in the reversal of bronchospasm in acute asthma attacks
  • Appropriate rescue medication should be available
  • Can be continued during acute exacerbations of asthma
  • Should not be abruptly substituted for inhaled or oral corticosteroids
  • Should not be used as monotherapy for the treatment and management of exercise induced bronchospasm
  • Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking M-K

Overdose Effects

  • Usual supportive measures should be employed in the event of overdose

Therapeutic Class

  • Leukotriene receptor antagonists

Storage Conditions

  • Store in cool & dry place below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C35H36ClNO3S

Common Questions about M-K 10 mg Tablet

  • Used to treat asthma or allergic rhinitis
  • Helps keep airways open and easy breathing by blocking leukotrienes
  • Effect can be observed after 1-3 hours of administration
  • Lasts for an average duration of 24 hours
  • May be taken with or without food as prescribed by doctor
  • Use in pregnant women should be avoided unless clearly needed

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