Stinba 10 mg (Tablet)

Indications

• Seasonal and Perennial Allergic Rhinitis
• Chronic Idiopathic Urticaria

Pharmacology

• Ebastine is a long-acting and selective H1-histamine receptor antagonist
• Inhibition of peripheral receptors remains at a constant level
• Rapid absorption and extensive first-pass metabolism following oral administration
• Almost totally converted to the pharmacologically active acid metabolite, carebastine

Dosage & Administration

• Tablet for Adults (more than 12 years of age): 10 mg (one tablet) once daily
• Tablet for Children (6-12 years of age): 5 mg (half tablet) once daily
• Syrup for Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases)
• Syrup for Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases)
• May be taken with or without food

Interaction

• Combination with ketoconazole or erythromycin increases plasma level of Stinba and prolonged QTc interval
• No interaction with the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam or alcohol
• Enhanced sedation effect of alcohol and diazepam

Contraindications

• Known hypersensitivity to Ebastine or any of its ingredients

Side Effects

• Most common: headache, dry mouth, drowsiness
• Less common: abdominal pain, dyspepsia, nausea, insomnia

Overdose Effects

• No clinically meaningful signs or symptoms observed up to 100 mg given once daily
• No specific antidote for Stinba
• In case of accidental overdoses: gastric lavage, monitoring of vital functions including ECG, symptomatic treatment

Therapeutic Class

• Non-sedating antihistamines

Storage Conditions

• Store below 30°C at a cool and dry place, away from light
• Keep out of reach of children

Related Brands

• Stinba 5 mg/5 ml (Syrup) - team-pharmaceuticals-ltd