Arnivas 97 mg+103 mg (Tablet)
Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sacubitril valsartan |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Reduction of cardiovascular risk
- Treatment of heart failure in pediatric patients
- Adjunct to other heart failure therapies
- Specified patient group indications
Pharmacology
- Contains neprilysin inhibitor and angiotensin receptor blocker
- Actions on neprilysin and angiotensin II
- Effects attributed to increased peptide levels and angiotensin II inhibition
Dosage & Administration
- Recommended starting dose for adults and pediatric patients
- Dose titration for pediatric patients based on weight
- Dose adjustments for renal and hepatic impairment
Interaction
- Dual blockade of the renin-angiotensin-aldosterone system
- Potential interactions with potassium-sparing diuretics, NSAIDs, and lithium
Contraindications
- Hypersensitivity to any component
- History of angioedema related to ACE inhibitor or ARB therapy
- Concomitant use of ACE inhibitors or aliskiren in diabetic patients
Side Effects
- Angioedema
- Hypotension
- Impaired Renal Function
- Hyperkalemia
- Cough
- Dizziness
Pregnancy & Lactation
- Unestablished safety and effectiveness in pediatric patients under 1 year
- No relevant pharmacokinetic differences observed in elderly patients
- No dose adjustment for mild hepatic impairment
- Not recommended in severe hepatic impairment
- Dose adjustment in renal impairment
Precautions & Warnings
- Risk of angioedema
- Potential for symptomatic hypotension
- Monitoring of serum creatinine and potassium levels
- Dosage reduction or interruption considerations
Use in Special Populations
- Unestablished safety and effectiveness in pediatric patients
- No relevant pharmacokinetic differences in elderly patients
- Dose adjustment for severe renal and hepatic impairment in adults
Overdose Effects
- Limited data available for human overdosage
- Potential hypotension
- Unlikelihood of removal by hemodialysis due to high protein binding
Storage Conditions
- Store below 30°C
- Protection from moisture
- Keep out of reach of children
Related Brands
- Arnivas 49 mg+51 mg (Tablet) - opsonin-pharma-ltd
- Arnivas 24 mg+26 mg (Tablet) - opsonin-pharma-ltd
- Sacutan 97 mg+103 mg (Tablet) - unimed-unihealth-pharmaceuticals-ltd
- Sacutan 49 mg+51 mg (Tablet) - unimed-unihealth-pharmaceuticals-ltd
- Sacutan 24 mg+26 mg (Tablet) - unimed-unihealth-pharmaceuticals-ltd