Hemocrit 3000 IU (IV/SC Injection)

3000 IU pre-filled syringe: ৳ 1,350.00

Medicine Details

Category	Details
Generic	Erythropoietin alfa
Company	Eskayef pharmaceuticals ltd
Also available as	Hemocrit 2000 iu injection Hemocrit 5000 iu injection

Indications

Treatment of anemia in Chronic Kidney Disease (CKD) patients
Anemia due to Zidovudine in HIV-infected patients
Effects of myelosuppressive chemotherapy
Reduction of allogeneic RBC transfusions in noncardiac, nonvascular surgery patients
Prevention of anemia of prematurity in infants with low birth weight

Description

Recombinant human erythropoietin (EPO) expressed in Chinese hamster ovary cells with a 165 amino acid sequence identical to human urinary EPO

Dosage

Evaluation of iron status before and during treatment
Monitoring hemoglobin levels at least weekly
Dose adjustment based on hemoglobin rate of rise and decline
Starting dose for CKD patients on dialysis and not on dialysis
Starting dose for Zidovudine-treated HIV-infected patients
Dose adjustment for patients on cancer chemotherapy

Administration

Do not shake or freeze
Protect syringe from light
Inspect visually for particulate matter before administration
Discard unused portions of EPO

Interaction

Potentiated effect by simultaneous therapeutic administration of haematinic agent like ferrous sulfate

Contraindications

Uncontrolled hypertension
Serious allergic reactions to EPO
Pure Red Cell Aplasia (PRCA) following EPO treatment

Side Effects

Hypertension, arthralgia, muscle spasm, pyrexia, dizziness, vascular occlusion
Cough, rash, injection site irritation
Nausea, vomiting, myalgia, stomatitis, weight decrease
Pruritus, headache, chills, deep vein thrombosis
Fall in serum ferritin values in premature infants

Pregnancy & Lactation

No adequate and well-controlled studies in pregnant women
Use in pregnancy only if potential benefit outweighs potential risk to fetus
Not recommended in pregnant or lactating surgical patients participating in autologous blood predonation program
Caution in nursing women

Overdose Effects

Can cause hemoglobin levels above desired level, managed with discontinuation or reduction of dosage and/or phlebotomy, severe hypertension observed following overdose

Therapeutic Class

Drugs for Haemolytic Hypoplastic & Renal Anemia

Storage Conditions

Store at 2°C to 8°C, do not freeze or shake, keep in original package to protect from light