Diloren 50 mg (Tablet)

Unit Price: ৳ 1.50 (10 x 10: ৳ 150.00)
Strip Price: ৳ 15.00

Medicine Details

Category Details
Generic Diclofenac sodium
Company Osl pharma limited
Also available as
Diloren 1 w gel Diloren sr 100 mg tablet

Indications

  • Rheumatology
  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive
  • Polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Spondylarthroses
  • Acute gout
  • Peri-articular rheumatic disorders
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for the prevention of pain, inflammation, and swelling
  • Post-operative and post-traumatic pain, inflammation, and swelling
  • Prevention of pain and treatment of inflammation and swelling of patients operated in the urogenital tract
  • Renal and biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug (NSAID)
  • Anti-rheumatic
  • Anti-inflammatory
  • Analgesic
  • Antipyretic
  • Uricosuric effect
  • Inhibits prostaglandin biosynthesis
  • Rapid and complete absorption from the gastro-intestinal tract
  • Metabolized in the liver
  • Undergoes first pass metabolism

Dosage & Administration

  • Diclofenac FC Tablet for Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food
  • Diclofenac SR Tablet for Adults: 1 tablet daily, taken whole with liquid, preferably at meal times
  • Diclofenac Dispersible Tablet for Adults: The recommended daily dosage is 2-3 tablets, maximum daily dose is 150 mg
  • Diclofenac TR Capsule: One capsule daily, to be taken preferably after mealtimes
  • Diclofenac Suppository for adults: 50 mg suppository 2-3 times daily, maximum daily dose is 150 mg
  • Diclofenac injection for adults: The usual dose is 1 ampoule daily, may be increased up to 2 ampoules daily in serious cases
  • Diclofenac Gel: Depending on the size of the area to be treated, 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily

Interaction

  • May increase plasma concentrations of lithium and digoxin
  • Isolated reports of an increased risk of haemorrhage with the combined use of diclofenac and anticoagulant therapy
  • Can be given together with oral antidiabetic agents without influencing their clinical effect
  • Cases of nephrotoxicity have been reported in patients receiving cyclosporin and diclofenac concomitantly
  • Serious toxicity when methotrexate and NSAIDs are given within 24 hours of each other
  • Convulsions may occur due to an interaction between quinolones and NSAIDs
  • Co-administration of diclofenac with other systemic NSAIDs and steroids may increase the frequency of unwanted effects

Contraindications

  • Hypersensitivity to any ingredient of the product
  • Peptic ulcer
  • Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
  • Contra-indicated in asthmatic patients in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor
  • Not to be used under occlusive airtight dressings

Side Effects

  • Adverse effects are mild, rare and transient
  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions such as rash and eczema
  • Local irritation and reddening of the skin
  • Skin rash

Pregnancy & Lactation

  • Should be employed only for compelling reasons during pregnancy
  • Lowest effective dose should be used during pregnancy
  • Not recommended during the first trimester of pregnancy
  • Not recommended during lactation

Precautions & Warnings

  • Rare instances of peptic ulceration or gastrointestinal bleeding
  • Advanced age patients should be kept under close observation
  • Avoid contact with eyes or mucus membranes after application
  • Hands should be washed properly after application
  • Not to be taken orally

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store in a cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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