Paragyl 400 mg (Tablet)

Unit Price: ৳ 1.06 (10 x 10: ৳ 106.00)
Strip Price: ৳ 10.60

Medicine Details

Category Details
Generic Metronidazole
Company Pristine pharmaceuticals ltd

Brand name

  • Paragyl

Therapeutic class

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

Indications

  • Prevention of post-operative infections due to anaerobic bacteria
  • Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis
  • Treatment of urogenital trichomoniasis
  • Bacterial vaginosis
  • Amoebiasis
  • Giardiasis
  • Acute ulcerative gingivitis
  • Anaerobically infected leg ulcers
  • Acute dental infections
  • Antibiotic associated pseudomembranus colitis

Pharmacology

  • Member of the imidazole class of antibacterial drug
  • Antiprotozoal agent
  • 5-nitro group interacts with DNA, giving bactericidal action

Dosage and administration

  • Multiple dosage regimens for different indications
  • Tablet, suspension, vaginal gel, suppository, IV infusion

Interaction

  • Disulfiram
  • Alcohol
  • Oral anticoagulant therapy
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

  • Hypersensitivity to Metronidazole or other Nitroimidazole derivatives

Side effects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

Pregnancy and lactation

  • Category B for pregnancy
  • Excretion in human milk
  • Caution advised during breastfeeding

Precautions and warnings

  • Regular monitoring for adverse reactions
  • Caution in hepatic encephalopathy patients
  • Possible urine darkening

Special populations

  • Hepatic impairment
  • Renal impairment

Overdose effects

  • Reported symptoms include vomiting, ataxia, slight disorientation
  • No specific antidote
  • Require symptomatic and supportive treatment

Storage conditions

  • Store below 30°C
  • Protected from light
  • Keep out of the reach of children
  • Do not use after expiry date

Common questions

  • What is Paragyl 400 mg Tablet?
  • What are the uses of Paragyl 400 mg Tablet?
  • What are the side effects of Paragyl 400 mg Tablet?
  • How long do I need to use Paragyl 400 mg Tablet before I see improvement of my conditions?
  • What are the contraindications to Paragyl 400 mg Tablet?
  • Is Paragyl 400 mg Tablet safe to use when pregnant?
  • Will Paragyl 400 mg Tablet be more effective if taken in more than the recommended dose?
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