Fluxagal 50 mg (Capsule)

Indications

• Vaginal Candidiasis
• Oropharyngeal Candidiasis
• Oesophageal Candidiasis
• Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
• Kerion
• Pityriasis versicolor
• Onychomycosis
• Invasive candidal infections and cryptococcal infections (including meningitis)
• Prevention of cryptococcal meningitis
• Prevention of fungal infections in immunocompromised patients
• Systemic Candidiasis and Cryptococcal infection
• Superficial Candidiasis
• Fungal urinary tract infections
• Disseminated candidiasis
• Prophylaxis for fungal infection in neutropenic cancer patients
• Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis

Pharmacology

Triazole antifungal agent, potent inhibitor of fungal cytochrome P-450 dependent enzymes, responsible for the synthesis of ergosterol

Dosage & Administration

• Adults
• Child over 1 year
• Use in Specific Population
• Elderly patient
• Renal Impairment

Interaction

Interactions with medications like warfarin, sulphonylureas, hydrochlorothiazide, phenytoin, rifampicin, combined oral contraceptives, cyclosporin, theophylline

Contraindications

Known hypersensitivity to Fluconazole or related triazole compounds

Side Effects

• Nausea
• Abdominal discomfort
• Diarrhoea
• Flatulence
• Rash
• Anaphylaxis

Pregnancy & Lactation

Adverse fetal effects seen in animals at dose levels associated with maternal toxicity, not recommended in pregnancy or lactation unless adequate contraception is employed

Precautions & Warnings

• Abnormalities in hepatic, renal, haematological, and other biochemical function tests
• Hepatic necrosis
• Exfoliative cutaneous reactions
• Use during lactation
• Driving/Use of machinery

Use in Special Populations

• Elderly
• Renal Impairment

Overdose Effects

Supportive measures, symptomatic treatment, gastric lavage if necessary

Related Brands

• Fluconazole 150 mg (Capsule) - biogen-pharmaceuticals-ltd