Esoxium 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Pristine pharmaceuticals ltd
Also available as
Esoxium 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase in the gastric parietal cell
  • High systemic bioavailability

Dosage

  • 20 mg or 40 mg once daily for 4-8 weeks for healing of erosive esophagitis
  • 20 mg once daily for maintenance of healing of erosive esophagitis
  • 20 mg once daily for symptomatic GERD
  • 40 mg once daily for Helicobacter pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for acid-related Dyspepsia
  • 20 mg once daily for 2-4 weeks for duodenal ulcer
  • 20-40 mg once daily for 4-8 weeks for gastric ulcer

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral suspension should be taken into a small glass containing 15 ml of water and stirred well
  • IV injection or infusion at specified dosages

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • Unlikely to inhibit multiple CYP enzymes
  • Potential interference with CYP2C19 for certain drugs
  • Clinically significant interactions with specific drug combinations

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Breastfeeding discontinuation if essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients
  • Antacids usage while taking Esoxium

Use in Special Populations

  • Safety and effectiveness not established in paediatric patients
  • No significant differences in safety and efficacy in the elderly
  • No recommended dosage adjustment for mild to moderate hepatic insufficiency
  • Expected renal impairment impact

Overdose Effects

  • Lethal to rats at high doses
  • Acute toxicity signs
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions about Esoxium 20 mg Capsule

  • Description of Esoxium 20 mg Capsule
  • Multiple uses
  • Common side effects
  • Usage during pregnancy and breastfeeding
  • Time to start working
  • Quick Tips

Related Brands