Etoricoxib 90 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Pain relief from dental surgery

Pharmacology

  • Potent COX-2 inhibitor
  • Orally active
  • Inhibition of prostaglandin-mediated functions
  • Selective inhibition of COX-2

Dosage & Administration

  • Recommended daily doses for different conditions
  • Possibility of dose increase for efficacy
  • Limitation on duration and maximum daily dose
  • Need for periodic re-evaluation of need for symptomatic relief

Interactions

  • Interaction with oral anticoagulants
  • Potential reduction in effect of diuretics and antihypertensive drugs
  • Compatibility with low-dose acetylsalicylic acid
  • Potential nephrotoxic effect with ciclosporin and tacrolimus
  • Impact on lithium plasma levels

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or gastrointestinal bleeding
  • Adverse reactions to acetylsalicylic acid or NSAIDs including COX-2 inhibitors
  • Pregnancy, lactation, severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Inflammatory bowel disease, congestive heart failure
  • Uncontrolled hypertension, established ischemic heart disease

Side Effects

  • Palpitation, fatigue, influenza-like symptoms
  • Ecchymosis, dry mouth, taste disturbance
  • Atrial fibrillation, transient ischemic attack
  • Anxiety, impaired mental acuity, electrolyte disturbance
  • Myalgia, arthralgia, confusion, hallucinations

Pregnancy & Lactation

  • Not recommended for women attempting to conceive
  • Excretion in lactating rats, not recommended for breastfeeding women

Precautions & Warnings

  • Caution in elderly and at-risk patients for gastrointestinal complications
  • Careful consideration for patients with significant cardiovascular risk factors
  • Risk of impaired renal function, caution in cardiac and edema patients
  • Monitoring of liver function, discontinuation upon hypersensitivity signs
  • Potential impact on fever and inflammation, caution with oral anticoagulants

Overdose Effects

No significant toxicity observed up to 500 mg single dose and 150 mg/day for 21 days

Therapeutic Class

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Temperature below 30°C, protection from light and moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg

Common Questions

  • Etoricoxib 90 mg Tablet:
    • Description: Selective COX-2 inhibitor for pain and inflammation relief
    • Duration of Effect: 20-24 hours
    • Onset of Action: 1-2 hours, faster without food
    • Pregnancy Warnings: Not recommended for pregnant women
    • Habit Forming: No reported tendencies
    • Breast-feeding Warnings: Not recommended for breast-feeding women
    • Safe with Alcohol: Unsafe to consume with alcohol
    • Safe to Drive: May affect alertness, avoid driving
    • Affect on Kidney Function: Caution and possible dose adjustment
    • Affect on Liver Function: Caution and possible dose adjustment
    • Quick Tips:
      • Helps relieve pain and inflammation
      • May cause fewer stomach problems compared to other NSAIDs
      • May cause dizziness and fatigue
      • Avoid alcohol consumption
      • Regular blood pressure monitoring
      • Inform doctor about medical history
      • Regular liver function tests during long-term treatment
      • Not recommended for pregnant or breastfeeding women

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