Pristical DX 600 mg+400 IU (Tablet)

Unit Price: ৳ 12.00 (1 x 30: ৳ 360.00)

Medicine Details

Indications

  • Treatment & prevention of Osteoporosis
  • Osteomalacia
  • Tetany
  • Hypoparathyroidism
  • Disorders of osteogenesis
  • Supplement for inadequate calcium intake in childhood diet
  • Rickets
  • Pregnancy & lactation
  • Pancreatitis
  • Phosphate binder in chronic renal failure

Composition

  • Each tablet contains Calcium Carbonate USP 1250 mg (Coral source) equivalent to 500 mg of elemental Calcium & Vitamin D USP 200 IU
  • Each DX tablet contains Calcium Carbonate USP 1500 mg (Coral source) equivalent to 600 mg of elemental Calcium & Vitamin D USP 400 IU
  • Each effervescent tablet contains Calcium Carbonate (Coral source) USP 1500 mg equivalent to 600 mg of elemental Calcium and Vitamin D3 400 IU as Cholecalciferol USP

Pharmacology

  • Adequate Calcium vital for various bodily functions
  • Clinical evidence of usefulness for Osteoporosis treatment & prevention
  • Vitamin D essential for healthy bones & Calcium absorption
  • Coral Calcium sourced for better absorption
  • Synergistic effects of Calcium & vitamin D on bone growth & fracture prevention

Dosage & Administration

  • One tablet once or twice daily with plenty of water or as directed by physician
  • Effervescent tablet to be dissolved in water and taken orally
  • Taking with full stomach ensures better absorption

Interaction

  • Thiazide diuretics reduce urinary excretion of calcium
  • Systemic corticosteroids reduce calcium absorption
  • Concomitant use with ion exchange resins may reduce vitamin D absorption
  • Interference with absorption of tetracycline preparations
  • Hypercalcaemia risk with cardiac glycosides
  • Need for time gap with foods high in oxalic acid and phytic acid

Contraindications

  • Hypercalcemia and hyperparathyroidism
  • Hypercalciuria and nephrolithiasis
  • Hypersensitivity to the component
  • Severe renal insufficiencies
  • Concomitant digoxin therapy

Side Effects

  • Irritation to GI tract
  • Constipation
  • Rarely produced hypercalcemia
  • Allergic reactions
  • Irregular heartbeats
  • Nausea
  • Vomiting
  • Decreased appetite
  • Dry mouth
  • Drowsiness
  • Skin rash reported with Vitamin D supplements

Pregnancy & Lactation

  • Caution in pregnancy to avoid overdoses' adverse effects on fetus
  • No indications of teratogenicity in humans
  • Caution in breast-feeding due to passage of Calcium and vitamin D3 into breast milk

Precautions & Warnings

  • Monitoring of serum calcium levels & renal function during long-term treatment
  • Caution in elderly patients on concomitant treatment with cardiac glycosides or diuretics
  • Risk of soft tissue calcification in patients with impaired renal function
  • Caution in immobilised patients with osteoporosis
  • Consideration of other vitamin D-containing drugs
  • Frequent monitoring of serum calcium levels and urinary calcium excretion

Overdose Effects

  • Hypervitaminosis D and hypercalcaemia
  • Symptoms include anorexia, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disturbances, polydipsia, polyuria, bone pain, nephrocalcinosis, nephrolithiasis, cardiac arrhythmias
  • Treatment involves discontinuation, rehydration, and monitoring of electrolytes and renal function

Therapeutic Class

Specific mineral & vitamin combined preparations

Storage Conditions

Store at temperature below 30°C, protect from light & moisture

Common Questions about Pristical DX 600 mg Tablet

  • Pristical DX 600 mg Tablet is for preventing & treating calcium and vitamin D deficiency
  • Benefits include prevention of osteoporosis, treatment of rickets, osteomalacia, and improvement of bone health in the elderly
  • Contraindications for individuals with high level of calcium or vitamin D, kidney stones, sarcoidosis, and allergies to ingredients
  • Common side effects include constipation, nausea, vomiting, diarrhea, headache, drowsiness, and dry mouth
  • Dosage is one tablet per day taken with food
  • Precautions advice against usage in pregnancy or breastfeeding, high levels of calcium or vitamin D, kidney stones, and allergies to ingredients

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