Prebalin CR 165 mg (Tablet (Extended Release))
Unit Price: ৳ 28.00 (2 x 10: ৳ 560.00)
Strip Price: ৳ 280.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day)
- Dosing should begin at 50 mg three times a day (150 mg/day)
- Maximum recommended dose of Pregabalin CR capsule is 330 mg once daily
- Recommended dose of Pregabalin is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day)
- Recommended dose of Pregabalin for fibromyalgia is 300 to 450 mg/day
- Recommended dose range of Pregabalin for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
- Conversion from Pregabalin capsules to Pregabalin CR capsule tablet
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Swallowed whole and should not be split, crushed or chewed
Drug interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
- Not applicable for food and others
Contraindications
- Patients with known hypersensitivity to Pregabalin or any of its components
Side effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention
- Increased weight and increased appetite in pediatric patients for the treatment of partial onset seizures
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin have been detected in the milk of lactating women
- Breastfeeding is not recommended during treatment with pregabalin
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise
- Hypersensitivity reactions
- Increase in risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- May cause dizziness and somnolence, impairing the ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
- May cause peripheral edema
- Coadministration with thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness in pediatric patients have not been established for various indications
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Confusional state
- Seizures
- Heart block
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions
- What is Prebalin CR 165 mg XR Tablet?
- How long do I need to use Prebalin CR 165 mg XR Tablet before I see improvement in my condition?
- At what frequency do I need to use Prebalin CR 165 mg XR Tablet?
- Should I use Prebalin CR 165 mg XR Tablet empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Prebalin CR 165 mg XR Tablet?
- Does Prebalin CR 165 mg XR Tablet work in the same way for each disease?
- How long do I need to take Prebalin CR 165 mg XR Tablet?
- Is it necessary to continue taking Prebalin CR 165 mg XR Tablet even if I feel fine?
- Can I take Diazepam and Prebalin CR 165 mg XR Tablet together?
- Can the use of Prebalin CR 165 mg XR Tablet cause weight gain?