Prolific 5000 IU/vial (IM/SC Injection)

5000 IU vial: ৳ 2,000.00

Medicine Details

Category Details
Generic Human chorionic gonadotrophin
Company Renata limited

Indications

  • Ovulation induction in infertility due to anovulation or impaired follicle-ripening (Female)
  • Preparation of follicles for puncture in controlled ovarian hyperstimulation programs (Female)
  • Luteal phase support (Female)
  • Threatened and habitual abortion (Female)
  • Hypogonadotropic hypogonadism (Male)
  • Delayed puberty associated with insufficient gonadotropic pituitary function (Male)
  • Cryptorchidism (Male)
  • Treatment of oligospermia (Male)

Pharmacology

  • Has LH activity
  • Stimulates Leydig cells to promote testosterone production (Male)

Dosage & Administration

  • Reconstituted solution administered intramuscularly
  • Ovulation induction and preparation of follicles for puncture
  • Luteal phase support
  • Threatened & habitual abortion
  • Hypogonadotropic hypogonadism

Interaction

  • No clinically relevant interactions known

Contraindications

  • Androgen-dependent tumors (Male)

Side Effects

  • Allergic reactions reported
  • Unwanted ovarian hyperstimulation syndrome (Female)
  • Water and sodium retention (Male)

Pregnancy & Lactation

  • Pregnancy Category X
  • Contraindicated in pregnant women
  • Not to be used during lactation

Precautions & Warnings

  • Increased risk of multiple births
  • Unwanted ovarian hyperstimulation risk
  • Ultrasonic assessment of follicular development advised

Use in Special Populations

  • Induction of precocious puberty in pediatric patients
  • Discontinue therapy if signs of precocious puberty occur (Pediatric Use)

Overdose Effects

  • Low acute toxicity

Therapeutic Class

  • Female sex hormones

Storage Conditions

  • Store at 2°C-8°C in refrigerator
  • Do not freeze
  • Store below 25°C for a single period of not more than 3 months
  • Protect from light and keep in dry place

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