Udiliva 300 mg (Tablet)
Unit Price: ৳ 35.00 (3 x 10: ৳ 1,050.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ursodeoxycholic acid |
| Company | Everest pharmaceuticals ltd |
| Also available as |
Title
- Udiliva
Categories
- Medicine
- Hepatobilliary Disorder Treatment
Description
- Reduces cholesterol saturation of bile
- Promotes dissolution of gallstones
- Reduces cholesterol absorption in bile
- Suppresses liver cholesterol synthesis
- Promotes formation of liquid cholesterol crystal complexes
Indications
- Cholestasis (Jaundice)
- Viral Hepatitis
- Alcoholic Fatty Liver
- Primary Billiary Cirrhosis (PBC)
- Primary Sclerosing Cholangitis (PSC)
- Dissolution of Gallstones
- Non-Alcoholic Steato Hepatitis (NASH)
Pharmacology
- Decrease in secretion of cholesterol in bile
- Reduces cholesterol absorption
- Suppresses liver cholesterol synthesis
- Promotes formation of liquid cholesterol crystal complexes
- Protects cholangiocytes against bile acids cytotoxicity
- Stimulates hepatobilliary secretion
- Protects hepatocytes against bile acid-induced apoptosis
- Completely absorbed in the upper intestine
- Biologic half life ranges from 3.5-5.8 days
Dosage and administration
- Dissolution of Gallstones: 8-12 mg/kg/day
- Primary Billiary Cirrhosis: 10-15 mg/kg/day in 2-4 divided doses
- Acute Viral Hepatitis: 600 mg/day
- Alcoholic Fatty Liver: 300 mg/day
- Primary Sclerosing Cholangitis: 25-30 mg/kg/day
- Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis: 13-15 mg/kg/day
Interaction
- Should not be used with oestrogenic hormones
- Avoid concomitant administration with bile-acid binding drugs such as antacids, charcoal, and cholestyramine
Contraindications
- Non-functioning gall-bladder
- Calcified and pigmented gallstones
- Inflammatory bowel disease
Side effects
- Nausea
- Vomiting
- Diarrhoea
- Gallstone opacilication
- Pruritus
Pregnancy and lactation
- Pregnancy category B
- Effectively used for the treatment of cholestasis of pregnancy during the last trimester without side effects
- No documented problems regarding breastfeeding
Precautions and warnings
- Should be used cautiously in those with liver disease
Therapeutic class
- Anti-gallstones drugs: Bile Acids
Storage conditions
- Store below 25°C
- Protected from light and moisture
- Keep out of the reach of children