Vorile 50 mg (Tablet)

Unit Price: ৳ 45.00 (1 x 10: ৳ 450.00)
Strip Price: ৳ 450.00

Medicine Details

Indications

  • Treatment of invasive aspergillosis
  • Candidemia treatment
  • Esophageal candidiasis treatment
  • Treatment for serious infections
  • Treatment for patients intolerant of other therapy

Pharmacology

  • Triazole antifungal medication
  • Binds and inhibits ergosterol synthesis
  • Inhibition of 14-alpha sterol demethylase
  • Depletion of ergosterol in fungal cell membrane

Dosage & Administration

  • Oral administration instructions for different body weights
  • Injection dosage for invasive aspergillosis, candidemia, scedosporiosis, and fusariosis

Interaction

  • Adjust dosage with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
  • Increase maintenance dosage with co-administration of Phenytoin or Efavirenz

Contraindications

  • Hypersensitivity to Voriconazole or any other components
  • Risk when co-administered with specific drugs

Side Effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy & Lactation

  • Use during pregnancy if potential benefit justifies potential risk to the fetus

Precautions & Warnings

  • Careful assessment for long-term exposure exceeding 180 days
  • Risk of squamous cell carcinoma of the skin (SCC)

Use in Special Populations

  • Efficacy not established in children under 12 years of age

Overdose Effects

  • No data available

Therapeutic Class

  • Other Antifungal preparations

Reconstitution

  • Instructions for suspension reconstitution
  • Storage and shelf-life of reconstituted suspension

Storage Conditions

  • Store in a dry place below 25°C, protected from light
  • Specific storage temperature for the powder for suspension

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