Vorile 200 mg/5 ml (Powder for Suspension)
40 ml bottle: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Euro pharma ltd |
| Also available as |
Indications and Usage
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by specific fungi
- Use in patients intolerant of or refractory to other therapy
Pharmacology
- Voriconazole is a triazole antifungal medication
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
- Results in depletion of ergosterol in fungal cell membrane
Dosage and Administration
- Oral and injection administration
- Dosage based on body weight
- Loading dose regimen for different indications
- Maintenance dose regimen for different indications
Interactions
- Interactions with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Potential impact on the concentrations and activity of other drugs
- Adjustment of Vorile dosage and monitoring for adverse reactions
Contraindications
- Known hypersensitivity to Voriconazole or any components
- Co-administration contraindications with specific drugs
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy and Lactation
- Limited data on use during pregnancy
- Consideration of potential benefit justifying potential risk to the fetus
Precautions and Warnings
- Careful assessment of benefit-risk balance for long-term exposure
- Reported association with squamous cell carcinoma of the skin with long-term treatment
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- Limited data available
Therapeutic Class
- Belongs to the therapeutic class of Other Antifungal preparations
Reconstitution Instructions
- Shake the bottle well before adding water to loosen the powder
- Specific instructions for adding water and storing reconstituted suspension
Storage Conditions
- Storage instructions for Vorile tablets and powder for suspension