Esozol 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company Medicon pharmaceuticals ltd
Also available as
Esozol 20 mg capsule Esozol 40 mg capsule

Title and Categories

  • Esozol 20 mg Tablet
  • Proton Pump Inhibitor (PPI)
  • Gastroesophageal Reflux Disease (GERD) Medication

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of duodenal and gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours
  • Metabolized in the liver by the cytochrome P450 (CYP) enzyme system

Dosage Forms

  • Tablet
  • Capsule
  • Oral Suspension
  • IV Injection
  • IV Infusion

Dosage Instructions

  • Different doses for various indications
  • Oral administration one hour before meals
  • IV infusion duration
  • Pediatric dosing based on body weight

Administration Instructions

  • Tablet or capsule should be swallowed whole
  • Oral suspension preparation and administration
  • IV injection preparation and administration

Interactions

  • Metabolism by CYP2C19 and CYP3A4
  • Inhibition of gastric acid secretion impacting drug absorption
  • No clinically significant interactions with certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth
  • No difference in types of related adverse events during maintenance treatment

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Discontinuation of breastfeeding if essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Instructions for patients with difficulty swallowing capsules
  • Use of antacids while taking Esozol

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed in geriatric use
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • Unaltered pharmacokinetics in renal impairment

Overdose Effects

  • Acute toxicity signs in animal studies
  • No reports of overdose in humans
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Dry place
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Commonly Asked Questions

  • Explanation of Esozol 20 mg Tablet
  • Uses, side effects, pregnancy and breastfeeding, onset of action
  • Quick tips for usage

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