Onride 4 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 50.00

Medicine Details

Category Details
Generic Ondansetron
Company Medicon pharmaceuticals ltd
Also available as

Title

  • Onride Oral Soluble Film

Category

  • Medicine
  • Pharmaceutical

Description

  • An orally dissolving film designed to be applied on top of the tongue where it will dissolve within 20 seconds and then is swallowed with saliva

Function

  • Prevention of nausea and vomiting associated with chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Active Ingredient

  • Ondansetron base

Molecular Weight

  • 293.3

Dosage Form

  • Oral Soluble Film
  • Tablet
  • Orodispersible Tablet
  • Injection
  • Oral Solution

Dosage Instructions

  • Adults, Pediatric patients (6 months to 18 years)
  • Adults
  • Pediatric patients (4-11 years)
  • Pediatrics (>40 kg)
  • Pediatrics (40 kg)

Dosage Adjustment

  • For Patients With Impaired Renal Function
  • For Patients With Impaired Hepatic Function
  • 4 years of age or younger
  • Over the age of 65

Pharmacological Action

  • Selective blocking agent of the serotonin 5-HT3 receptor type

Administration Instructions

  • Tear the pouch carefully along with the edge tear mark
  • Put the film on top of your tongue
  • Swallow after the film dissolves
  • Wash your hands after taking the film

Interactions

  • Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes
  • Inducers or inhibitors of these enzymes may change the clearance and half-life

Contraindications

  • Hypersensitivity to the drug or any of its components
  • Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Sensation of flushing or warmth
  • Hiccups
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Bronchospasm
  • Tachycardia
  • Angina (chest pain)
  • Hypokalemia
  • Shortness of breath

Pregnancy & Lactation

  • No evidence of impaired fertility or harm to the fetus in animal studies
  • Excreted in the breast milk of rats
  • Caution should be exercised when administered to a nursing women

Precautions & Warnings

  • Hypersensitivity reactions reported in patients hypersensitive to other selective 5-HT3 receptor antagonists
  • Not to be used in place of nasogastric suction
  • May mask a progressive ileus and/or gastric distension

Special Populations

  • Dosage adjustment for patients with impaired renal function
  • Dosage adjustment for patients with impaired hepatic function
  • Little information available about dosage in pediatric patients 4 years of age or younger
  • No dosage adjustment needed in patients over the age of 65

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Store at temperature not exceeding 30°C in a dry place
  • Protect from light and moisture

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