Nepitan 49 mg+51 mg (Tablet)
Unit Price: ৳ 85.00 (1 x 10: ৳ 850.00)
Strip Price: ৳ 850.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sacubitril valsartan |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Reduces risk of cardiovascular death
- Hospitalization for heart failure
- Treatment of symptomatic heart failure
- Administered in conjunction with other heart failure therapies
Pharmacology
- Contains neprilysin inhibitor
- Contains sacubitril
- Contains angiotensin receptor blocker
- Inhibits neprilysin
- Blocks angiotensin II type-1 receptor
Dosage & Administration
- Recommended starting dose for adults
- Recommended maintenance dose for adults
- Recommended dose for pediatric patients
- Dose titration guidelines
- Dose adjustment for renal impairment
- Dose adjustment for hepatic impairment
Interaction
- Dual blockade of the Renin-Angiotensin-Aldosterone System
- Interactions with potassium-sparing diuretics
- Interactions with NSAIDs
- Interactions with Lithium
Contraindications
- Hypersensitivity to any component
- History of angioedema related to previous ACE inhibitor or ARB therapy
- Concomitant use of ACE inhibitors
- Concomitant use of aliskiren in patients with diabetes
Side Effects
- Angioedema
- Hypotension
- Impaired Renal Function
- Hyperkalemia
- Cough
- Dizziness
Pregnancy & Lactation
- Safety and effectiveness in pediatric patients
- Relevance to geriatric use
- Dose adjustment for hepatic impairment
- Dose adjustment for renal impairment
Precautions & Warnings
- May cause angioedema
- Low blood pressure
- Symptomatic hypotension
- Monitoring serum creatinine
- Monitoring serum potassium
Use in Special Populations
- Safety and effectiveness in pediatric patients
- Relevance to geriatric use
- Dose adjustment for renal impairment
- Dose adjustment for hepatic impairment
Overdose Effects
- Limited data on overdosage
- Possible hypotension
- Symptomatic treatment
- Unlikely to be removed by hemodialysis
Storage Conditions
- Dry place for storage
- Store below 30°C
- Protection from moisture
- Keep out of the reach of children